Results 61 to 70 of about 994,929 (290)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Parameter Selection of Local Search Algorithm for Design Optimization of Automotive Rubber Bumper

open access: yesApplied Sciences, 2020
In rubber bumper design, the most important mechanical property of the product is the force–displacement curve under compression and its fulfillment requires an iterative design method.
Dávid Huri, Tamás Mankovits
doaj   +1 more source

Fundamental investigation on free-form optimization of vibration lures

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Lure fishing is a special fishing method that using artificial fishing lures as fish baits and has become more and more popular all over the world. Vibration lures are a regular item among fishing lures that perform vibration action in the water for ...
Jin-Xing SHI   +2 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Shape optimization of joining interface profile for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials

open access: yesNihon Kikai Gakkai ronbunshu, 2021
The shape optimization of joining interface profile is performed for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials.
Hideki SEKINE, Hiroshi SHIRAHATA
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Fully turbulent discrete adjoint solver for non-ideal compressible flow applications

open access: yesJournal of the Global Power and Propulsion Society, 2017
Non-Ideal Compressible Fluid-Dynamics (NICFD) has recently been established as a sector of fluid mechanics dealing with the flows of dense vapors, supercritical fluids, and two-phase fluids, whose properties significantly depart from those of the ideal ...
Salvatore Vitale   +4 more
doaj   +1 more source

Non-Parametric Shape Optimization of a Football Boot Bottom Plate

open access: yesProceedings, 2020
This paper describes the non-parametric shape optimization process for a football boot bottom plate. The non-parametric shape optimization process changes the nodes’ location of a model and outputs an optimum shape, which satisfies an optimization ...
Jeong-Ro Lee   +2 more
doaj   +1 more source

Optimal Motion of an Articulated Body in a Perfect Fluid [PDF]

open access: yes, 2005
An articulated body can propel and steer itself in a perfect fluid by changing its shape only. Our strategy for motion planning for the submerged body is based on finding the optimal shape changes that produce a desired net locomotion; that is ...
Kanso, Eva, Marsden, Jerrold E.
core  

Global optimization of complex optical structures using Baysian optimization based on Gaussian processes

open access: yes, 2017
Numerical simulation of complex optical structures enables their optimization with respect to specific objectives. Often, optimization is done by multiple successive parameter scans, which are time consuming and computationally expensive.
Burger, S.   +3 more
core   +1 more source

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