Results 61 to 70 of about 1,014,609 (340)

Parameter Selection of Local Search Algorithm for Design Optimization of Automotive Rubber Bumper

open access: yesApplied Sciences, 2020
In rubber bumper design, the most important mechanical property of the product is the force–displacement curve under compression and its fulfillment requires an iterative design method.
Dávid Huri, Tamás Mankovits
doaj   +1 more source

Fundamental investigation on free-form optimization of vibration lures

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Lure fishing is a special fishing method that using artificial fishing lures as fish baits and has become more and more popular all over the world. Vibration lures are a regular item among fishing lures that perform vibration action in the water for ...
Jin-Xing SHI   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Shape optimization of joining interface profile for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials

open access: yesNihon Kikai Gakkai ronbunshu, 2021
The shape optimization of joining interface profile is performed for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials.
Hideki SEKINE, Hiroshi SHIRAHATA
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Fully turbulent discrete adjoint solver for non-ideal compressible flow applications

open access: yesJournal of the Global Power and Propulsion Society, 2017
Non-Ideal Compressible Fluid-Dynamics (NICFD) has recently been established as a sector of fluid mechanics dealing with the flows of dense vapors, supercritical fluids, and two-phase fluids, whose properties significantly depart from those of the ideal ...
Salvatore Vitale   +4 more
doaj   +1 more source

Non-Parametric Shape Optimization of a Football Boot Bottom Plate

open access: yesProceedings, 2020
This paper describes the non-parametric shape optimization process for a football boot bottom plate. The non-parametric shape optimization process changes the nodes’ location of a model and outputs an optimum shape, which satisfies an optimization ...
Jeong-Ro Lee   +2 more
doaj   +1 more source

Global optimization of complex optical structures using Baysian optimization based on Gaussian processes

open access: yes, 2017
Numerical simulation of complex optical structures enables their optimization with respect to specific objectives. Often, optimization is done by multiple successive parameter scans, which are time consuming and computationally expensive.
Burger, S.   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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