Results 71 to 80 of about 1,975,441 (290)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

具有简单G3条件的可调曲线曲面(Adjustable curves and surfaces with simple G3 conditions)

Zhejiang Daxue xuebao. Lixue ban, 2016
In order to make curves and surfaces have adjustable shape and simple G3 conditions,a kind of EI functions is defined recursively. Based on them, we construct EI curves and surfaces,which have the most properties of Bézier curves and surfaces. Owe to the
YANLanlan(严兰兰), YINGZhengwei(应正卫)   +1 more
doaj   +1 more source

Reliability evaluation and analysis of sugarcane 7000 series harvesters in sugarcane harvesting [PDF]

Journal of Agricultural Machinery, 2015
Introduction: The performance of agricultural machines depends on the reliability of the equipment used, the maintenance efficiency, the operation process, the technical expertise of workers, etc.
P Najafi, M. A Asoodar, A Marzban, M. A Hormozi   +3 more
doaj   +1 more source

Inference on the Parameters of the Weibull Distribution Using Records [PDF]

, 2015
The Weibull distribution is a very applicable model for the lifetime data. In this paper, we have investigated inference on the parameters of Weibull distribution based on record values.
Jafari, Ali Akbar, Zakerzadeh, Hojatollah   +1 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Evidence for Non‐Stationarity in the GEV Shape Parameter When Modeling Extreme Rainfall

Water Resources Research
It is now well established that climate change is increasing the intensity of extreme rainfall. What is less well established is how best to model these changes.
Lalani Jayaweera, Conrad Wasko, Rory Nathan   +2 more
doaj   +1 more source

Collective Path Connecting the Oblate and Prolate Local Minima in 68Se

, 2004
By means of the adiabatic self-consistent collective coordinate method and the pairing plus quadrupole interaction, we have obtained the selfconsistent collective path connecting the oblate and prolate local minima in 68Se for the first time.
Almehed, Baranger, Bengtsson, Duguet, Fischer, Kenichi Matsuyanagi, Kobayasi, Kobayasi, Marumori, Masato Kobayasi, Masayuki Matsuo, Matsuo, Petrovici, Takashi Nakatsukasa, Yamagami   +14 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Study on Dynamic Factors of Damped Beam Members Under Exponential Attenuation Loading

Buildings
Blast loading is characterized as an impact loading with exponential attenuation, while damping serves as an intrinsic parameter that affects the vibration effect of beam members. The linear attenuation for simplified blast loading and undamped situation
Xin Hong, Shaobo Geng, Rui Feng
doaj   +1 more source