Results 151 to 160 of about 871,984 (313)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Geometric shape parameterization of multidimensional finite non-regular point sets
Омский научный вестникThe paper is devoted to a formal approach to parameterization the geometric shape of spatial point irregular sets in multidimensional Euclidean space.
V. Yu. Yurkov, M. A. Chizhik
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
PARTICULARITIES OF PREPARING FOR A MAJOR COMPETITION IN WOMEN’S 800M RACE – CASE STUDY
Sport şi Societate, 2014 Getting (acquiring) and maintaining the athletic shape for a period that includes the most important competition of a training season are among the essential issues of modern sports training methodology.
Ursanu Grigore
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Conditioning Factors of Linearized Wood's Function Lactation Curve Shape Parameters, Milk Yield, Fat and Protein Content in Murciano-Granadina Primiparous Does. [PDF]
Animals (Basel), 2020 Delgado Bermejo JV +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
A Novel Gamma Distributed Random Variable (RV) Generation Method for Clutter Simulation with Non-Integral Shape Parameters. [PDF]
Sensors (Basel), 2020 Chen S, Luo F, Hu C.
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Bezier curves and surfaces with shape parameters
, 2009 NSFC [10571145]Bezier curves with n shape parameters and triangular Bezier surfaces with 3n(n+1)/2 shape parameters are presented in this paper. The geometric significance of the shape parameters and the geometric properties of these curves and surfaces ...
曾晓明, Zeng, X. M., Yang, L. Q.
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