Results 111 to 120 of about 1,451,088 (294)
Sharing a Stage in the Arena of Agency
Erasmus StudiesAbstract Exactly five hundred years ago today, Erasmus engaged with Martin Luther in a debate on free will that continues to inspire, even if it evokes a notion of freedom that is no longer ours in every respect. Emphasising the need for a common-sense reading of Holy Scripture that did not require making conjectures about the existence of hidden ...
openaire +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Cahiers Mondes Anciens, 2019 Agamemnon’s excuses in book 19 of the Iliad have been considered very problematic for the understanding of action and its attribution to several agents in Homer. In this paper, I analyze how the king seeks to convince his audience by presenting his deeds
Manon Brouillet
doaj +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
What helps or hinders practitioners, children and young people, and their families in implementing the Common Assessment Framework and Lead Professional working? [PDF]
, 2009 The Every Child Matters (DfES 2003) policy agenda has brought multi-agency working to the fore of children’s services in the UK. The implementation of the Common Assessment Framework (CAF) is a central part of the measures developed to improve outcomes ...
Crossland, Ruth
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Informazioni ambientali sempre più condivise
GEOmedia, 2010 SEIS: Shared Enviroment and Information System The Shared Environmental Information System (SEIS) is a collaborative initiative of the European Commission and the European Environment Agency (EEA) to establish together with the Member States an ...
Mauro Salvemini
doaj +2 more sources
Equipping Police with Naloxone Spray and Decriminalizing All Opioid Use in the U.S.: An Ethical Analysis [PDF]
, 2018 The number of police departments carrying Narcan keeps increasing at a fast pace throughout the U.S., as it is considered an effective measure to fight the opioid epidemic. However, there have been strong oppositions to the idea of the police Narcan use.
Lee, Marvin J. H.
core
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source