Results 81 to 90 of about 205,273 (284)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Inter-agency Cooperation and New Approaches to Employability [PDF]
, 2008 This article examines the role of inter-agency cooperation, which is one form of ‘partnership’, in new approaches to employability in the UK. The article articulates a ‘model for effective partnership working’ on employability.
Dutton, Matthew +5 more
core +1 more source
Cognitive Hybridization: Redefining Human Identity at the Interface of Neuroscience and Artificial Intelligence: A Narrative Review [PDF]
Journal of Advanced Biomedical SciencesBackground & Objective: The convergence of human cognition and artificial intelligence (AI) is reshaping cognitive identity and challenging traditional understandings of consciousness, agency, and selfhood.
Seyed Mahmoud Tabatabaei, Sanaz Khalili
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Vermont Agency of Transportation 2022 Research Peer Exchange [PDF]
PS0947The Vermont Agency of Transportation (Vermont AOT) hosted a virtual peer exchange on June 7, 14 and 21, 2022, to discuss topics related to transportation research with other state departments of transportation (DOTs). The meeting and the subsequent
Seeber, Kirsten +2 more
core
Płodność działalności planowanej
Ethics in Progress, 2013 As normal adult human agents we have a remarkable trio of capacities. First, we are capable of acting over time in ways that involve important forms of intentional cross-temporal organization and coordination.
Michael E. Bratman
doaj +3 more sources
Practical Intersubjectivity and Normative Guidance: Bratman on Shared Agency
Journal of Social Ontology, 2014 In an important new book on shared agency, Michael Bratman develops an account of the normative demand for the coordination of intentions amongst participants in shared agency. Bratman seeks to understand this form of normative guidance in terms of that
Abraham Sesshu Roth
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Shared goals in science education: youth agency across three national systems
Eesti Haridusteaduste AjakiriLoodusteadusliku hariduse puhul puutuvad eri riigid pidevalt kokku probleemiga, kuidas säilitada noorte huvi loodusainete vastu, tagades samas, et nende ainepõhised nõuded saaksid rangelt täidetud.
Angie Valbuena Rojas +2 more
doaj +3 more sources
Emerging Microbes and InfectionsCarbapenemase-producing Enterobacter (CP-Ent) are the third most prevalent species of CP-Enterobacteriaceae worldwide and exhibit greater strain diversity than other CP-species.
Conrad Izydorczyk +19 more
doaj +1 more source