Results 51 to 60 of about 33,398 (247)

Continue, adjust, or stop antipsychotic medication: developing and user testing an encounter decision aid for people with first-episode and long-term psychosis

BMC Psychiatry, 2018
Background People with psychosis struggle with decisions about their use of antipsychotics. They often want to reduce the dose or stop, while facing uncertainty regarding the effects these decisions will have on their treatment and recovery.
Yaara Zisman-Ilani, David Shern, Patricia Deegan, Julie Kreyenbuhl, Lisa Dixon, Robert Drake, William Torrey, Manish Mishra, Ksenia Gorbenko, Glyn Elwyn   +9 more
doaj   +1 more source

Visual Responsivity in Autism: Measuring Visual Responses in Autistic and Non‐Autistic Adults Using Psychophysics, fMRI, and EEG

Autism Research, EarlyView.
ABSTRACT Autistic individuals frequently report heightened sensitivity to visual stimuli, often described as discomfort in environments with bright or flickering lights. These experiences are hypothesized to reflect underlying differences in sensory gain or neural hyperexcitability; however, findings across studies have yielded mixed results, likely ...
Daniela L. Seczon, Kristin M. Woodard, Tamar Kolodny, Hannah M. Rea, Mark Pettet, Sara Jane Webb, Scott O. Murray   +6 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Barriers to shared decision making in mental health care: qualitative study of the Joint Crisis Plan for psychosis [PDF]

Health Expectations, 2015
AbstractBackgroundDespite increasing calls for shared decision making (SDM), the precise mechanisms for its attainment are unclear. Sharing decisions in mental health care may be especially complex. Fluctuations in service user capacity and significant power differences are particular barriers.Objective and designWe trialled a form of facilitated SDM ...
Farrelly, Simone, Lester, Helen, Rose, Diana, Birchwood, Max, Marshall, Max, Waheed, Waquas, Henderson, R. Claire, Szmukler, George, Thornicroft, Graham   +8 more
openaire   +5 more sources

Shared lexical-semantic features and the animacy effect in early-course psychosis

, 2019
Language deficits in psychosis, and in schizophrenia, are presumed to be due to increased activation and connectivity of the semantic memory, which is determined by lexical-semantic features of concepts. The aim of this study was to analyse the influence of shared lexical semantic features on language processing in patients with first-episode and early-
Martina Sekulić Sović, Vlasta Erdeljac, Iva Kužina, Mija Vandek, Ninoslav Mimica, Draženka Ostojić, Aleksandar Savić   +6 more
openaire   +3 more sources

Standardization of measurement and reporting of medication adherence using the TEN‐SPIDERS tool for claims data

British Journal of Clinical Pharmacology, EarlyView.
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori, Tzu‐Yung Kuo, Jenni Ilomäki, Monique F. Kilkenny, Stella Talic, Zanfina Ademi, J. Simon Bell, Jedidiah I. Morton, Lachlan L. Dalli   +8 more
wiley   +1 more source

COllaborative Shared care to IMprove Psychosis Outcome (COSIMPO): study protocol for a randomized controlled trial [PDF]

Trials, 2017
Psychotic disorders are a group of severe mental disorders that cause considerable disability to sufferers and a high level of burden to families. In many low- and middle-income countries (LMIC), traditional and faith healers are the main providers of care to affected persons.
Oye Gureje, Victor Makanjuola, Lola Kola, Bidemi Yusuf, LeShawndra N. Price, Oluyomi Esan, Bibilola D. Oladeji, John Appiah-Poku, Benjamin Haris, Caleb Othieno, Soraya Seedat   +10 more
openaire   +4 more sources

Ethnic minority inequalities in access to treatments for schizophrenia and schizoaffective disorders: findings from a nationally representative cross-sectional study

BMC Medicine, 2018
Background Ethnic minority service users with schizophrenia and schizoaffective disorders may experience inequalities in care. There have been no recent studies assessing access to evidence-based treatments for psychosis amongst the main ethnic minority ...
Jayati Das-Munshi, Dinesh Bhugra, Mike J. Crawford   +2 more
doaj   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Integrating biological pathway polygenic scores and trauma in psychosis: findings from the EU-GEI study

Translational Psychiatry
Psychotic disorders are complex, multifactorial conditions influenced by both genetic liability and early environmental adversity. Polygenic risk scores (PRSs) derived from genome-wide association studies have shown utility in capturing genetic ...
Giulia Trotta, Isabelle Austin-Zimmerman, Edoardo Spinazzola, Lucia Sideli, Monica Aas, Victoria Rodriguez, Senta Haussler, Zhikun Li, Perry BM Leung, Qiang Li, Diego Quattrone, Teya Petrova, Craig Morgan, Michael O’Donovan, Pak C. Sham, Evangelos Vassos, Chloe CY Wong, Richard Bentall, Robin M. Murray, Luis Alameda, Marta Di Forti   +20 more
doaj   +1 more source