Results 71 to 80 of about 1,490,078 (257)

Clinical importance of the 5-Step Precision Medicine (5SPM) method in shared decision-making to choose the antipsychotic treatment for a patient with first-episode psychosis: a case report

open access: yesBMC Psychiatry
Background Adverse effects can disrupt early treatment in first-episode psychosis and precipitate discontinuation. We report the use of the five-step precision medicine (5SPM) method in personalised precision psychiatry to guide antipsychotic decision ...
Óscar Gonzalo   +10 more
doaj   +1 more source

A latent class analysis of positive psychosis symptoms based on the British Psychiatric Morbidity Survey [PDF]

open access: yes, 2007
This study aimed to describe the distribution of positive psychosis symptoms in a large scale, population-based sample. Data from the British Psychiatric Morbidity Survey was used to examine homogeneous sub-types of participants based on their responses ...
Shevlin, M, Adamson, G, Murphy, J
core   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask   +6 more
wiley   +1 more source

Co-occurring eating disorder and psychosis: a lived experience case exploration with examples and suggestions for personalized integrated treatment approach

open access: yesJournal of Eating Disorders
Disordered eating or eating disorders (ED) and psychosis commonly co-occur and have a degree of overlap, however there are no current clinical guidelines or comprehensive clinical guidance for integrated treatment.
Rosiel Elwyn
doaj   +1 more source

Cannabis and psychosis : the Maltese contribution [PDF]

open access: yes, 2010
Three different Maltese scientists have contributed to research on the link between cannabis and psychosis. The object of this article is to review and chronicle the work that has been done by these three colleagues in this field.
Agius, Mark   +2 more
core  

Pharmacogenomics of dolutegravir: A scoping review of evidence, gaps and clinical implications

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Dolutegravir underpins modern first‐ and second‐line HIV treatment regimens; however, interindividual variability in its disposition and tolerability presents challenges for optimal use. This scoping review mapped current evidence on the pharmacogenomics of dolutegravir, focusing on pharmacokinetics and pharmacodynamics, and methodological limitations ...
Ronald Kiguba   +2 more
wiley   +1 more source

The interpersonal self in early-onset psychosis : a grounded theory analysis [PDF]

open access: yes, 2005
The prodromal phase has been conceptualised as a discrete phase in the disease process relevant for its ‘warning’ status. Recent psychological and medical research has suggested that intervention during this period may be beneficial.
Taylor, Emily; id_orcid   +1 more
core  

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

Psychosis or the ineffable space of modernism [PDF]

open access: yes, 2013
The aim of this psychoanalytic reflection on architecture is to disengage the spatial image from space, and thereby to reclaim for space its symbolic and contingent status.
Holm, Lorens Eyan; id_orcid
core   +1 more source

Experiences of Prisoners Living With Mental Health Conditions and Seeking or Receiving Mental Health Support in Prisons: An Integrative Review

open access: yesCriminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Prisoners experience poor mental health and well‐being in prison, including severe mental illnesses. However, access to mental health support and treatment in prison is limited. We conducted an integrative review to synthesise prisoners' experiences of living with mental ill health and/or seeking or receiving mental health support ...
Anne Kairu   +5 more
wiley   +1 more source

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