Results 61 to 70 of about 1,490,078 (257)

Understanding suicidal ideation in psychosis: findings from the Psychological Prevention of Relapse in Psychosis (PRP) trial [PDF]

, 2006
Objective: To examine the clinically important phenomenon of suicidal ideation in psychosis in relation to affective processes and the multidimensional nature of hallucinations and delusions.Method: In a cross-sectional study of 290 individuals with ...
Garety, PA, Bebbington, P E, Freeman, D, L. Fialko, Dunn, G., Dunn, G, Bebbington, PE, D. Fowler, Fowler, D. G., Fialko, L, G. Dunn, Garety, P A; id_orcid, Kuipers, E; id_orcid, Fowler, D, Fialko, L., Kuipers, E, E. Kuipers, Freeman, D., Bebbington, P. E., Freeman, Daniel, D. Freeman, P. E. Bebbington, P. A. Garety, Garety, P. A., Kuipers, E.   +24 more
core   +1 more source

Standardization of measurement and reporting of medication adherence using the TEN‐SPIDERS tool for claims data

British Journal of Clinical Pharmacology, EarlyView.
This study provides the first open‐source tool to implement the complete TEN‐SPIDERS framework in linked datasets for the determination of the PDC for medication adherence. The TEN‐SPIDERS tool enables transparent, reproducible medication adherence research through automated reporting of all calculation parameters and flexible customization options ...
Adam C. Livori, Tzu‐Yung Kuo, Jenni Ilomäki, Monique F. Kilkenny, Stella Talic, Zanfina Ademi, J. Simon Bell, Jedidiah I. Morton, Lachlan L. Dalli   +8 more
wiley   +1 more source

Integrating biological pathway polygenic scores and trauma in psychosis: findings from the EU-GEI study

Translational Psychiatry
Psychotic disorders are complex, multifactorial conditions influenced by both genetic liability and early environmental adversity. Polygenic risk scores (PRSs) derived from genome-wide association studies have shown utility in capturing genetic ...
Giulia Trotta, Isabelle Austin-Zimmerman, Edoardo Spinazzola, Lucia Sideli, Monica Aas, Victoria Rodriguez, Senta Haussler, Zhikun Li, Perry BM Leung, Qiang Li, Diego Quattrone, Teya Petrova, Craig Morgan, Michael O’Donovan, Pak C. Sham, Evangelos Vassos, Chloe CY Wong, Richard Bentall, Robin M. Murray, Luis Alameda, Marta Di Forti   +20 more
doaj   +1 more source

Social and spatial heterogeneity in psychosis proneness in a multilevel case-prodrome-control study [PDF]

, 2015
To test whether spatial and social neighbourhood patterning of people at ultra-high risk (UHR) of psychosis differs from first-episode psychosis (FEP) participants or controls and to determine whether exposure to different social environments is evident ...
Metastasio, A, Theegala, S, Aguilar, E, Crane, CM, Webster, R, Kirkbride, JB, Jones, PB, Perez, J, Stochl, J, Kabacs, N, Zimbrón, J   +10 more
core  

Protocol for a systematic review and meta-analysis of cognitive-behavioural therapy for social anxiety disorder in psychosis [PDF]

, 2014
Background: Social anxiety is among the most prevalent and debilitating affective disturbances manifest in people with psychosis. It is usually accompanied by high levels of depression and leads to significant social disability, lower quality of life ...
Michail, M.; id_orcid, Max Birchwood, Michail, Maria, Maria Michail, Lynda Tait, Birchwood, M., Tait, L., Birchwood, M. J., Tait, Lynda   +8 more
core   +2 more sources

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Exploring the role of TNF-α, TGF-β, and IL-6 serum levels in categorical and noncategorical models of mood and psychosis

Scientific Reports
Psychotic and mood disorders are discussed as part of the same continuum. The potential role of immune dysregulation in defining their clinical presentations, however, remains unclear.
Maja Pantovic-Stefanovic, Milica Velimirovic, Vladimir Jurisic, Marija Puric, Marta Gostiljac, Sara Dodic, Ivana Minic, Milica Nesic, Tatjana Nikolic, Natasa Petronijevic, Maja Ivkovic, Bojana Dunjic-Kostic   +11 more
doaj   +1 more source

Resistant Schizoaffective Disorder in a Patient with Psoriasis and Hypophysitis: A Case Report of the Interaction Between Psychosis and Chronic Systemic Inflammation

Psychiatry International
Schizoaffective disorder is a complex psychiatric condition that often requires specialized treatment, particularly when resistant to standard therapies.
Rui Martins Pinhel, Irina Gorgal Carvalho, Francisco Coutinho, Martim Luz, Rita Dionísio, Rui Vilarinho, Palmira Coya   +6 more
doaj   +1 more source

Early Psychosis Intervention in an Asian Context: a decade of Real-life developments and outcomes in Hong Kong

, 2014
Early Intervention Programs worldwide are guided by a set of common frameworks. They include early detection through reduction of duration of untreated psychosis, provision of phase specific intervention to optimise outcomes in the critical period, as ...
Chen, EYH
core  

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source