Results 111 to 120 of about 1,665,329 (315)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Contracts, cost sharing and consistency [PDF]

open access: yes
Under a contract, agents are not only held to honor the allocation as prescribed by a cost sharing mechanism but also a full description of allocated units and costs once production falls short. For agents leaving the cost sharing problem by taking their
Koster, M.
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Are people willing to share living space? Household preferences in Finland

open access: yesBuildings & Cities
This paper explores citizens’ interest in space sharing in private housing. It is based on a large-scale random sample citizen survey (N = 1448) conducted in Finland focusing on multiple aspects of low-carbon housing. Both quantitative preference-related
Enni Ruokamo   +3 more
doaj   +1 more source

Resource Sharing News (Fall 2000 : volume 2, number 2)

open access: yes, 2000
Document Delivery Staff begin new work processes; New Service Levels let you choose how Minitex handles your requests; Document Delivery Website Grows; Dear Del Illa; New Digs - Better Delivery Service?Minitex Resource Sharing. (2000).
Minitex Resource Sharing
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The neighbourhood home: An environments system from sharing to caring

open access: yesDiscern, 2021
Cities are changing. Wars, climate change and idealised better life opportunities open the doors for massive migration. Unfortunately, however, the new arrivals with their different backgrounds and lifestyles are often perceived as a threat to pre ...
Ilaria Longo   +2 more
doaj  

Sequential Sharing Rules for River Sharing Problems [PDF]

open access: yes
We analyse the redistribution of a resource among agents who have claims to the resource and who are ordered linearly. A well known example of this particular situation is the river sharing problem.
Hans-Peter Weikard, Erik Ansink
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A Brief Overview of the Pawns Programming Language

open access: yesSoftware
This paper describes the Pawns programming language, currently under development, which uses several novel features to combine the functional and imperative programming paradigms.
Lee Naish
doaj   +1 more source

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