Results 121 to 130 of about 2,275,625 (264)
Equilibrium unemployment under negotiated profit sharing [PDF]
We study employment, employee effort, wages and profit sharing when firms face stochastic revenue shocks and when base wages and profit shares are determined through collective bargaining.
Rune Stenbacka, Erkki Koskela
core +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Strategic Outsourcing, Profit Sharing and Equilibrium Unemployment [PDF]
We analyze the following questions associated with outsourcing and profit sharing under imperfect labour markets. How does strategic outsourcing influence wage formation, profit sharing and employee effort when firms commit to optimal profit sharing ...
König, Jan, Koskela, Erkki
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Estudi sobre les necessitats de renda als municipis de l'Àrea Metropolitana de Barcelona
, 2018 L'objectiu d'aquest estudi és determinar quines són les necessitats de renda existents als diferents municipis de l'àrea metropolitana de Barcelona, quina és la seva capacitat de fer-hi front i analitzar possibles maneres d'articular-ne el finançament ...
Knowledge Sharing Network (Firma)
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
What explains Hadza food sharing? [PDF]
Most hypotheses proposed to explain human food sharing address motives, yet most tests of these hypotheses have measured only the patterns of food transfer. To choose between these hypotheses we need to measure peopleç—´ propensity to share.
F.W. Marlowe
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Resource Sharing News (Winter 2002 : volume 4, number 1)
, 2002 Table of Contents: A Look at What's Going on in Electronic Delivery; Minitex is Now a Distributor of Ariel Software; Delivery News; Eleventh Annual Minitex Interlibrary Loan Conference; Meet the MOD Squad; MnLINK User Group Meeting; Dear Del Illa ...
Minitex Resource Sharing
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source