Results 131 to 140 of about 1,665,329 (315)
Flexible Outsourcing, Profit Sharing and Equilibrium Unemployment [PDF]
We analyze the questions associated with flexible outsourcing both with committed and flexible profit sharing under imperfect domestic labour markets. How does profit sharing influence flexible outsourcing?
Erkki Koskela, Jan König
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
What explains Hadza food sharing? [PDF]
Most hypotheses proposed to explain human food sharing address motives, yet most tests of these hypotheses have measured only the patterns of food transfer. To choose between these hypotheses we need to measure peopleç—´ propensity to share.
F.W. Marlowe
core
Industry and Public Sector Cooperation for Information Sharing: Ports of the Puget Sound [PDF]
, 2009 This report presents the findings of the Maritime Information Sharing Taskforce (MIST) research effort for the Washington State Puget Sound ports. Using a participatory design approach, the researchers partnered with federal and commercial stakeholders ...
Englehorn, Lyla +2 more
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Strategic Outsourcing, Profit Sharing and Equilibrium Unemployment [PDF]
We analyze the following questions associated with outsourcing and profit sharing under imperfect labour markets. How does strategic outsourcing influence wage formation, profit sharing and employee effort when firms commit to optimal profit sharing ...
König, Jan, Koskela, Erkki
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Understanding Public Attitudes to Bike-Sharing in Gothenburg
, 2014 A predominately car-oriented transport has been the cornerstone of urban development in a worldwide scale for decades now; a cornerstone that is associated mostly with the short-term individualistic benefit of the road user in terms of comfort and ...
Nikitas, Alexandros, Wallgren, Pontus
core
Publishing and sharing sensitive data [PDF]
, 2014 Sensitive data has often been excluded from discussions about data publication and sharing. It was believed that sharing sensitive data is not ethical or that it is too difficult to do safely.
Sarah Olesen
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source