Results 101 to 110 of about 18,650 (200)

Causal association of sex hormone-related traits with Alzheimer’s disease: a multivariable and network Mendelian randomization analysis

Frontiers in Neurology
BackgroundAlthough studies have demonstrated a correlation between sex hormone-related traits [such as sex hormone binding globulin (SHBG) and testosterone] and Alzheimer’s Disease (AD), the link remains uncertain due to the intricacies of AD pathology ...
Yan Zhang, Zhen-dong Sun, Yu-shen Yang, Wei-dong Fu   +3 more
doaj   +1 more source

Higher Serum Testosterone Protects Against the Development of Type 2 Diabetes in Middle‐Aged but Not Older Men

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6959-6964, August 2026.
ABSTRACT Background Low serum testosterone concentration has been reported to be causally linked to the risk of Type 2 diabetes (T2D). The benefit of T2D protection has been demonstrated to continue up to serum testosterone concentrations of 461 ng/dL (16 nmol/L).
Mahesh M. Umapathysivam, Andrew D. Vincent, Jason Tan, Alebachew Ashagre, David Jesudason, Gary Wittert   +5 more
wiley   +1 more source

Short‐Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open‐Label, Randomised Controlled Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7380-7392, August 2026.
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang, Yuxin Xu, Hu Du, Wenya Liu, Haiyan Chen, Dongfang Liu, Lili Zhang, Cong Wang   +7 more
wiley   +1 more source

Association between sex hormone binding globulin and metabolic syndrome in US adults: insights from National Health and Nutrition Examination Survey (NHANES) 2013–2016

Diabetology & Metabolic Syndrome
Background Metabolic syndrome (MetS) presents a notable public health challenge on a global scale, exerting a considerable impact on individuals’ health and quality of life.
Yang Yang, Jie Wang, Yi Huang, Yuhang Liu, Shuwan Liu, Huabao Liu, Meiao Tan   +6 more
doaj   +1 more source

Investigating the Mediating Role of Cardiometabolic Traits in the Causal Link Between SHBG Levels and Stroke Risk via Network Mendelian Randomization

Current Issues in Molecular Biology
The causal nature of sex hormone-binding globulin (SHBG) in the pathogenesis of stroke remains uncertain. We explored whether SHBG levels are causally associated with stroke via cardiometabolic traits.
Peijiang Pan, Hao Liang, Mingli Li
doaj   +1 more source

[Changes of SHBG concentrations in postmenopausal women].

Ginekologia polska, 2002
Sex hormone-binding globulin (SHBG) is a serum (serous) glycoprotein binding estrogens and androgens with high affinity. Hepatic synthesis of SHBG and serous protein concentration are related to the following factors: age, sex steroids and thyroid hormones concentrations, obesity.
P, Skałba, A, Korfanty, W, Mroczka, M, Wójtowicz   +3 more
openaire   +1 more source

Salivary estradiol and progesterone across the menstrual cycle: Association and agreement with serum concentrations

Physiological Reports, Volume 14, Issue 15, August 2026.
Abstract Saliva provides a noninvasive alternative to serum for serial sampling of estradiol and progesterone. This study examined salivary estradiol and progesterone patterns and the relationship between salivary and serum estradiol, progesterone, and the estradiol to progesterone ratio (E2:P) across the menstrual cycle (MC) in physically active ...
Samantha J. Goldenstein, Emily E. Bechke, Sandra J. Shultz, Catherine McDowell, Laurie Wideman   +4 more
wiley   +1 more source

Intermittent exogenous ketosis increases erythropoietin in healthy adults: A randomized, placebo‐controlled study with preliminary sex‐specific observations

Physiological Reports, Volume 14, Issue 15, August 2026.
Intermittent exogenous ketosis stimulates erythropoietin, with greater EPO response and elevated ferritin in females but no significant changes in circulating hemoglobin or red blood cell count at 2 weeks. Abstract Exogenous ketosis may stimulate erythropoietin (EPO), yet its impact on erythropoiesis, iron metabolism, and potential sex‐specific ...
Henrik Holm Thomsen, Birgitte Sandfeld‐Paulsen, Lise Nørkjær Bjerg, Jesper Nørgaard Bech   +3 more
wiley   +1 more source

Assessing the causal relationship between frailty and sex hormone-binding globulin or insulin-like growth factor-1 levels: A sex-stratified bidirectional Mendelian Randomization study

Experimental Gerontology
Background: The association between frailty and sex hormone-binding globulin (SHBG) or insulin-like growth factor-1(IGF-1) levels demonstrates sex differences with inconsistent conclusions.
Xinying Fan, Yuxin Wang, Zhaoyu Zhang, Runjun Yang, Yajing Zhou, Jie Gu   +5 more
doaj   +1 more source

SHBG wt Allele [PDF]

, 2020
openaire   +1 more source