Results 91 to 100 of about 18,650 (200)

Circulating Sex Hormone Levels and Survival in Men With Esophageal Squamous Cell Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Men with esophageal squamous cell carcinoma (ESCC) have worse survival than women, a disparity in which sex hormones may play a role. Yet, whether circulating sex hormone levels are associated with survival in ESCC remains largely unexplored.
Zhiqiang Liu   +7 more
wiley   +1 more source

Association Between SHBG Levels and Hypertensive Disorders of Pregnancy: A Systematic Review and Meta‐Analysis

open access: yesThe Journal of Clinical Hypertension
Sex hormone‐binding globulin (SHBG) regulates sex hormone availability and is influenced by metabolic factors. Variations in SHBG levels during pregnancy may affect the development of hypertensive disorders such as gestational hypertension (GH) and ...
Ajay Malvi   +19 more
doaj   +1 more source

Impact of Metformin Use on Clinical and Pathological Outcomes in Breast Cancer Patients With Type 2 Diabetes

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. Type 2 diabetes mellitus (T2DM) is a significant comorbidity in patients with breast cancer that negatively affects prognosis. Metformin, a first‐line antidiabetic drug, has been suggested to possess antineoplastic properties. This study
Ensiyeh Bahadoran   +4 more
wiley   +1 more source

Study on the Effects and Mechanisms of Sea Buckthorn Fruit Pulp in Improving Polycystic Ovary Syndrome

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Sea buckthorn pulp improves metabolic and reproductive dysfunction in a letrozole‐induced PCOS mouse model and is associated with modulation of the PI3K/AKT/mTOR signaling pathway. ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder characterized by ovarian dysfunction, hyperandrogenism, and insulin resistance.
Han Xiaoya   +9 more
wiley   +1 more source

Association of Testosterone With Lean Soft Tissue and Handgrip Strength Across Middle‐Aged Men

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Testosterone declines by 0.4%–2% annually after the age of 30 and is potentially linked with muscle mass and strength. This study examined how testosterone levels are associated with handgrip strength (HGS) and appendicular lean soft tissue index (ALSTI) in men aged 40–49 and 50–59 years.
Konstantinos Prokopidis   +6 more
wiley   +1 more source

Association of sex hormone-binding globulin and dyslipidemia with Japanese postmenopausal women: a cross-sectional study

open access: yesLipids in Health and Disease
Background In postmenopausal women, lower levels of sex hormone-binding globulin (SHBG) have been linked to various metabolic conditions. The association between SHBG levels and the presence of dyslipidemia was investigated in comparison with other sex ...
Takahiro Ichikawa   +11 more
doaj   +1 more source

Low Levels of Sex Hormone-Binding Globulin Constitute an Independent Risk Factor for Arterial Stiffness in Korean Women

open access: yesInternational Journal of Endocrinology, 2017
The association between sex hormone-binding globulin (SHBG) and arterial stiffness in women is not conclusive. In addition, obesity might also be involved in the relationship between SHBG and atherosclerosis.
Kunhee Han   +8 more
doaj   +1 more source

Insulin Resistance Emerges Early After Glucocorticoid Treatment in Adult Patients With 21‐Hydroxylase Deficiency

open access: yesJournal of Diabetes, Volume 18, Issue 8, August 2026.
In adults with 21‐hydroxylase deficiency, ongoing glucocorticoid therapy, especially dexamethasone, was the main risk factor for insulin resistance. New‐onset insulin resistance emerged early, highlighting the need for metabolic monitoring within the first 1–2 years of treatment. ABSTRACT Background Metabolic disorders, particularly insulin resistance (
Chenchen Dong   +8 more
wiley   +1 more source

Supplementary material for "SHBG gene polymorphisms and their influence on serum SHBG, total and free testosterone concentrations in men".

open access: yes
Supplementary material for JCEM submission titled "SHBG gene polymorphisms and their influence on serum SHBG, total and free testosterone concentrations in men".
Walravens, Joeri   +11 more
openaire   +1 more source

Metabolic Phenotype Predicts Biochemical Response to Inositol Supplementation in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

open access: yesClinical Endocrinology, Volume 105, Issue 2, Page 237-244, August 2026.
ABSTRACT Objective To evaluate the effect of inositol supplementation on biochemical hyperandrogenism in women with polycystic ovary syndrome (PCOS) and to explore whether metabolic phenotype modifies the endocrine response. Design Systematic review and meta‐analysis of randomized controlled trials conducted in accordance with PRISMA guidelines ...
Daniele Tienforti   +10 more
wiley   +1 more source

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