Results 71 to 80 of about 19,253 (201)

Koroner Kalp Hastası Erkeklerde SHBG Geni (TAAAA)n Pentanükleotid Tekrar Sayılarının Serum SHBG ve Lipid Düzeyleri Üzerine Etkisi

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2017
Amaç: Yüksek yoğunluklu lipoprotein-kolesterol (HDL-K) seviyelerinin önemli düzenleyicilerinden biri cinsiyet hormonlarıdır. Cinsiyet hormon bağlayıcı globülin (SHBG), biyoaktif serbest cinsiyet hormonlarını belirleyen bir faktördür.
Hülya Yılmaz Aydoğan, Beyhan Ömer, Zehra Buğra, Başak Akadam Teker, Özlem Kurnaz Gömleksiz   +4 more
doaj  

Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features

Andrology, EarlyView.
ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao, Gabriel Cabreira Nunes, Manuela Almeida Ribeiro, Luiza Costa da Fonseca, Aline Cristina Miranda Marinho Costa, Mateus Rodrigues Westin, Unai Tupinambas, Milena Maria Moreira Guimaraes, Leticia Ferreira Gontijo Silveira   +8 more
wiley   +1 more source

An HMMR-derived SHBG genetic score predicts lower type 2 diabetes risk

Regenesis Repair Rehabilitation
Background: Circulating sex hormone–binding globulin (SHBG) is associated with insulin resistance and cardiometabolic disease, yet causality, sex differences and genetic determinants remain unclear.
Jinhong Zhuang, Cun Ku, Manni Wu, Jiyu Xie, Chenhang Li, Zichun Qin, Abdrakhmanov Ayan, Jianlei Zheng, Yang Zhang   +8 more
doaj   +1 more source

Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang, Can Zhang, Chunlai Yang, Baosen Meng, Xiaohui Li, Qian Huang, Baibing Mi   +6 more
wiley   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle, Christine Lefevre, Simon Boussion, Cindy Colson, Iva Gueorguieva, Francois Marcelli, Anne Laure Barbotin, Pascal Pigny, Hamza Benderradji, Clara Leroy   +9 more
wiley   +1 more source

Lower SHBG level is associated with higher leptin and lower adiponectin levels as well as metabolic syndrome, independent of testosterone

Scientific Reports, 2017
In addition to testosterone (T), the emerging role of sex hormone-binding globulin (SHBG) in pathogenesis of metabolic syndrome (MetS) has been noted recently. However, reports of associations with serum adipocytokine levels are still limited. Therefore,
Chia-Chu Liu, Shu-Pin Huang, Kai-Hung Cheng, Tusty-Jiuan Hsieh, Chun-Nung Huang, Chii-Jye Wang, Hsin-Chih Yeh, Chia-Chun Tsai, Bo-Ying Bao, Wen-Jeng Wu, Yung-Chin Lee   +10 more
doaj   +1 more source

SHBG concentration in hyperthyroid patients

Periodicum biologorum, 1989
SHBG concentration in hyperthyroid patients is discussed.
Nothig-Hus, Dunja, Spaventi, Šime, Lukinac, Ljerka, Kusić, Zvonko   +3 more
openaire   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

Clinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams, Bonnie Grant, Richard Quinton, Channa N. Jayasena   +3 more
wiley   +1 more source

Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms

Open Life Sciences
Sex hormone-binding globulin (SHBG) is a serum glycoprotein exhibiting the unique feature of binding sex steroids with high affinity and specificity.
Zhao Shuhang, Gu Jiaojiao, Tian Yu, Wang Ruoyan, Li Wentao   +4 more
doaj   +1 more source

Nonlinear association of sex hormone-binding globulin levels and chronic kidney disease, an analysis based on the National Health and Nutrition Examination Survey (NHANES) 2013–2016

Renal Failure
Studies on the relationship between serum sex hormone-binding globulin (SHBG) levels and chronic kidney disease (CKD) remain limited and inconclusive.
Qi Zhang, Li Yang, Lin Zhou, Xiaoqin Xin
doaj   +1 more source