Results 81 to 90 of about 18,650 (200)

Association of sex hormone-binding globulin with nonalcoholic fatty liver disease in Chinese adults

open access: yesNutrition & Metabolism, 2018
Background Sex hormone-binding globulin (SHBG), a glycoprotein synthesized by hepatocytes, has been linked to insulin resistance and hepatic lipid metabolism and is suggested to be associated with nonalcoholic fatty liver disease (NAFLD).
Jing Luo   +9 more
doaj   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

open access: yesBMC Genetics, 2018
Background Levels of sex hormone-binding globulin (SHBG) and the androgen testosterone have been associated with risk of diseases throughout the lifecourse.
Ryan Arathimos   +4 more
doaj   +1 more source

Anti‐Müllerian Hormone and Metabolic–Hormonal Profiles in Women With and Without Polycystic Ovary Syndrome: A Population‐Based Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani   +5 more
wiley   +1 more source

AMH in combination with SHBG for the diagnosis of polycystic ovary syndrome

open access: yesJournal of Obstetrics and Gynaecology, 2019
Serum Anti-Müllerian hormone (AMH) level could be useful for the diagnosis of polycystic ovary syndrome (PCOS). We evaluated the hormonal status in women for the diagnosis of PCOS. A total of 77 PCOS women and 106 healthy women were enrolled in this study.
Mireya, Calzada   +7 more
openaire   +2 more sources

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

open access: yesAndrology, Volume 14, Issue 6, Page 1504-1514, September 2026.
ABSTRACT Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier   +8 more
wiley   +1 more source

Parental Educational Attainment at Birth and Biomarkers of Male Fecundity: A Study From the Danish National Birth Cohort

open access: yesAndrology, Volume 14, Issue 6, Page 1560-1569, September 2026.
ABSTRACT Background Low parental education is associated with poorer offspring health, but its influence on male fecundity remains unclear. Objective To study the association between parental educational attainment at birth and biomarkers of male fecundity in young men and to explore whether this association is mediated by maternal smoking in pregnancy
Anne Hjorth Thomsen   +6 more
wiley   +1 more source

SHBG levels correlate with insulin resistance in postmenopausal women

open access: yesEuropean Journal of Internal Medicine, 2009
Overweight or central obesity is generally associated with increases in fasting insulin levels, insulin resistance, and glucose intolerance and has been identified as a target for new therapeutic strategies, including early change in lifestyle. Early biochemical markers for identifying at-risk patients will be useful for prevention studies.
Akın, Hatice Fulya   +3 more
openaire   +7 more sources

Low Free Testosterone Is Independently Associated With Long‐Term Mortality in Men With Chronic Spinal Cord Injury

open access: yesAndrology, Volume 14, Issue 6, Page 1712-1722, September 2026.
ABSTRACT Background Testosterone deficiency is highly prevalent in men with chronic spinal cord injury (SCI) and is associated with obesity, sarcopenia, systemic inflammation, and metabolic dysfunction. However, the independent prognostic role of low testosterone in long‐term mortality in this population remains unclear.
D. Tienforti   +8 more
wiley   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen   +14 more
wiley   +1 more source

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