Results 41 to 50 of about 8,822,461 (241)

Prediction of Shear Strength for Steel-Fiber High-Strength Concrete Corbels with the Softened Strut-and-Tie Model

open access: yesBuildings, 2023
On the basis of the test results of nine steel-fiber high-strength concrete corbel specimens subjected to a vertical load, the influence of the steel fiber content on the shear performance of corbels was analyzed.
Shu-Shan Li   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Finite Element Analysis of the Shear Performance of Reinforced Concrete Corbels under Different Design Codes

open access: yesBuildings
This study aimed to investigate the shear performance of reinforced concrete corbels and to evaluate the accuracy and safety of the Chinese code GB 50010-2010’s triangular truss model and the American code ACI 318-19’s strut-and-tie model under various ...
Yuan Huang, Leilei Peng, Hanlin Wei
doaj   +1 more source

Shear Mechanism of High-Strength-Friction-Grip Bolts in Steel and Steel-Fiber-Reinforced-Concrete Composite Beams

open access: yesFrontiers in Materials, 2022
Steel and steel-fiber-reinforced concrete (SFRC) composite beams with high-strength friction-grip bolt (HSFGB) connectors have been found to improve the shear behavior of HSFGBs and enhance the potential application of composite beams.
Yujie Zhang   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Numerical Investigation of the Pull-Out and Shear Mechanical Characteristics and Support Effectiveness of Yielding Bolt in a Soft Rock Tunnel

open access: yesApplied Sciences
Conventional bolts frequently fail under large deformations due to stress concentration in soft rock tunnels. In contrast, yielding bolts incorporate energy-absorbing mechanisms to sustain controlled plastic deformation.
Yan Zhu   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Design and Evaluation of a Single-Span Bridge Using Ultra- High Performance Concrete;TR-529, September 2009 [PDF]

open access: yes, 2009
Research presented herein describes an application of a newly developed material called Ultra-High Performance Concrete (UHPC) to a single-span bridge. The two primary objectives of this research were to develop a shear design procedure for possible code

core  

Study on the Shear Performance of Steel-to-Timber Glued-in Rod Connections

open access: yesBuildings
Glued-in rod (GIR) connections are widely used in timber composite structures owing to their high load-bearing capacity, high stiffness, and concealed configuration.
Miao Pang   +3 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

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