Results 31 to 40 of about 127,098 (302)

Simultaneous Absolute Timing of the Crab Pulsar at Radio and Optical Wavelengths [PDF]

, 2008
The Crab pulsar emits across a large part of the electromagnetic spectrum. Determining the time delay between the emission at different wavelengths will allow to better constrain the site and mechanism of the emission. We have simultaneously observed the
A. Golden, A. Stankov, C. Erd, Cocke, Cognard, D. D. E. Martin, Dyks, Eikenberry, Golden, Hankins, Hewish, Hobbs, I. Cognard, J. A. Stüwe, Kanbach, Karpov, Kuiper, Lyne, Oosterbroek, P. Verhoeve, Percival, R. Schulz, Ramachandran, Romani, Romani, Rots, Shearer, Sollerman, Staelin, T. Ho, T. Oosterbroek, Takata   +31 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Innovation design service platform of shearer

Gong-kuang zidonghua, 2019
In view of problems of dispersive design data and difficult knowledge sharing existed in current shearer design, an innovation design service platform of shearer was developed. The platform utilizes key technologies such as dedicated web crawler based on
YANG Huaiyu, DING Hua, YANG Kun
doaj   +1 more source

Longwall shearer tracking system [PDF]

, 1984
A tracking system for measuring and recording the movements of a longwall shearer vehicle includes an optical tracking assembly carried at one end of a desired vehicle path and a retroreflector assembly carried by the vehicle.
Pease, R. E., Poulsen, P. D., Stein, R. J.   +2 more
core   +1 more source

A new method for determining small earthquake source parameters using short-period P waves [PDF]

, 2007
We developed a new technique of inverting short-period (0.5–2 Hz) P waveforms for determining small earthquake (M
Helmberger, Don, Tan, Ying
core   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Strength analysis of shearer body based on ansys

Metalurgija, 2023
Taking a certain type of shearer as the research object, using the large-scale Finite Element Analysis (FEA) software ANSYS, according to the actual situation of load distribution, the stress model of the shearer body is established, the stress and ...
T. Q. He, Y. Gao, L. Y. Huang, Z. J. Xue
doaj  

Coal-rock recognition and control system of shearer based on vibration characteristics analysis

Gong-kuang zidonghua, 2015
In order to solve problems of coal-rock recognition and automatic height regulation control of shearer during cutting process, a kind of coal-rock recognition and control system of shearer was put forward and designed which was based on vibration ...
WANG Shuisheng
doaj   +1 more source