A field study evaluating the humoral immune response in Mongolian sheep vaccinated against sheeppox virus [PDF]
AbstractSheeppox is a transboundary disease of small ruminants caused by infection with the capripoxvirus sheeppox virus. Sheeppox is found in Africa, the Middle East and Asia and is characterized by fever, multifocal cutaneous raised lesions and death.
Fay, Petra +10 more
openaire +4 more sources
Modulation of macrophage functions by sheeppox virus provides clues to understand interaction of the virus with host immune system [PDF]
Background Poxviruses encode a range of immunomodulatory genes to subvert or evade the challenges posed by the innate and adaptive immune responses. However, the inactivated poxviruses possessed immunostimulating capacity and were used as a prophylactic ...
Abdel-Moneim Ahmed S +1 more
doaj +3 more sources
Production of the Bakırköy strain of sheeppox vaccine virus in spinner flasks using an alternative method with Cytodex 1 microcarriers on Vero cells [PDF]
Background Sheeppox (SPP) is a highly contagious viral disease that causes significant morbidity and economic losses in small ruminants. Effective control relies on widespread vaccination, yet conventional production methods that utilize monolayer ...
Görkem Çolak +2 more
doaj +2 more sources
Epidemiological, Pathological, and Molecular Studies on Sheeppox Disease Outbreaks in Karnataka, India [PDF]
An epidemiological study spanning twelve years has revealed that sheeppox disease is both widespread and endemic, predominantly surging during the winter and summer seasons.
Gundallahalli Bayyappa Manjunatha Reddy +6 more
doaj +2 more sources
Molecular characterisation of lumpy skin disease virus and sheeppox virus based on P32 gene [PDF]
Lumpy skin disease virus (LSDV) and sheeppox virus (SPV) have a considerable economic impact on the cattle and small ruminant industry. They are listed in group A of contagious disease by the World Organization for Animal Health (OIE).
P.M.A.Rashid +3 more
doaj +2 more sources
Different Neutralizing Antibody Responses of Heterologous Sera on Sheeppox and Lumpy Skin Disease Viruses [PDF]
Sheeppox virus (SPPV), goatpox virus (GTPV), and lumpy skin disease virus (LSDV) are the three members of the genus Capripoxvirus within the Poxviridae family and are the etiologic agents of sheeppox (SPP), goatpox (GTP), and lumpy skin disease (LSD ...
Francisco J. Berguido +6 more
doaj +2 more sources
Sheeppox virus genome sequences from the European outbreaks in Spain, Bulgaria, and Greece in 2022-2024. [PDF]
In 2022-2024, three outbreaks of sheeppox (SPP) were reported in the European Union. These occurred in Spain, Bulgaria, and Greece and had serious economic consequences due to animal losses and trade restrictions. Five sheeppox virus (SPPV) whole-genome sequences (WGSs) were determined from samples collected during these outbreaks and analyzed in the ...
Breman FC +14 more
europepmc +3 more sources
Development of a potential vaccine against Capripox virus implementing reverse vaccinology and pan-genomic immunoinformatics. [PDF]
CPXV is responsible for animal diseases affecting cattle (Lumpy Skin Disease), sheep (Sheeppox), and goats (Goatpox). During outbreaks, these diseases have huge socio-economic effects.
Md Mohaimenul Islam Tareq +9 more
doaj +2 more sources
Molecular Determinants of Species-Specific Interactions Between Protein Kinase R and Poxvirus K3 Orthologs [PDF]
Protein kinase R (PKR) is an antiviral protein that is involved in molecular “arms races” with viral antagonists. As a result, some PKR inhibitors, including the vaccinia virus (VACV) protein K3 and its orthologs from other poxviruses only inhibit PKRs ...
Chorong Park +6 more
doaj +2 more sources
Metagenomic profiling of viral and microbial communities from the pox lesions of lumpy skin disease virus and sheeppox virus-infected hosts [PDF]
IntroductionIt has been recognized that capripoxvirus infections have a strong cutaneous tropism with the manifestation of skin lesions in the form of nodules and scabs in the respective hosts, followed by necrosis and sloughing off. Considering that the
Fedor S. Sharko +16 more
doaj +2 more sources

