Results 61 to 70 of about 1,031 (146)

A Genome‐Wide Screening of Novel Immunogenic TrLSDV103 Protein of Lumpy Skin Disease Virus and Its Application for DIVA

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Using the VirScan platform covering 4522 LSDV protein sequences, sera from 20 LSDV‐infected and 20 GTPV‐vaccinated cattle were used to screen phage libraries. Sequencing and bioinformatics analyses revealed peptides covering the TrLSDV103 protein. The candidate antigen was subsequently expressed, confirmed for its DIVA capability, and used to develop ...
Xinwei Yuan, Junhua Dong, Zhijie Xiang, Qian Zhang, Pan Tao, Aizhen Guo   +5 more
wiley   +1 more source

Production and assessment of polyclonal antibody against the whole virion of Goatpox virus and sheeppox virus in the rabbit [PDF]

, 2019
Abstract Abstract Background: Antibodies have emerged as essential tools of biomedical researches and are of great commercial and medical values. They are the fastest growing product segments of the pharmaceutical industry. Polyclonal antibodies are antibodies that secreted by different B cell lineages within the body.
Zhizhong Jing, Takele Tesgera Hurisa, Huaijie Jia, Guohua Chen, Fang Yong Xiang, Xiao-Bing He, Xia oxia Wang   +6 more
openaire   +1 more source

Replication and Virulence in Cattle of the First Lumpy Skin Disease Virus Isolated in Xinjiang, China (2019)

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Before 2012, lumpy skin disease (LSD) was primarily confined to African countries. However, it rapidly spread to the Middle East and Southeast Europe, reaching the Balkans, the Caucasus, and the Russian Federation by 2015. The first confirmed case in China was reported on August 10, 2019, in Yili, Xinjiang, and on August 26, the Chinese government ...
Minmin Zhang, Shaohan Li, Yujie Shi, Xiaolong Xu, Zhiyuan Wen, Jinying Ge, Qiwei Zhang, Xinyin Lu, Xin Yin, Zhigao Bu, Nan-hua Chen   +10 more
wiley   +1 more source

Development of a potential vaccine against Capripox virus implementing reverse vaccinology and pan-genomic immunoinformatics.

PLoS ONE
CPXV is responsible for animal diseases affecting cattle (Lumpy Skin Disease), sheep (Sheeppox), and goats (Goatpox). During outbreaks, these diseases have huge socio-economic effects.
Md Mohaimenul Islam Tareq, Sattyajit Biswas, Farazi Abinash Rahman, Labib Sharirar Siam, Sadia Jannat Tauhida, Shamim Ahmed, Hasan Jafre Shovon, Mariya Ahmed, Kazi Afrin Jerin, Md Nazmul Hasan   +9 more
doaj   +1 more source

Genetic Evolutionary Analysis of Lumpy Skin Disease Virus Strain Under Immune Pressure Exerted by Heterologous Goat Poxvirus Vaccines

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Lumpy skin disease (LSD) is an important infectious disease that threatens the global cattle industry. Recently, LSD has occurred frequently in Asia. The attenuated goat poxvirus (GTPV) vaccine is widely used to prevent LSD in cattle in China; however, sporadic cases of LSD still occur in immunized cattle.
Wenchi Chang, Junyang Fang, Tianshu Zhai, Shuizhong Han, Wenqi Fan, Congshang Lei, Lizhen Wang, Xuefeng Qi, Qinghong Xue, Jingyu Wang, Nan-hua Chen   +10 more
wiley   +1 more source

Complete Coding Sequence of a Novel Bluetongue Virus Isolated from a Commercial Sheeppox Vaccine

Microbiology Resource Announcements, 2020
The full genome sequences of two isolates of bluetongue virus (BTV) from a commercial sheeppox vaccine were determined. Strain SPvvvv/02 shows low sequence identity to its closest relative, strain BTV-26 KUW2010/02, indicating the probable detection of a novel BTV genotype, whereas strain SPvvvv/03 shows high sequence identity to strain BTV-28/1537/14.
Rajko-Nenow, Paulina, Golender, Natalia, Bumbarov, Velizar, Brown, Hannah, Frost, Lorraine, Darpel, Karin, Tennakoon, Chandana, Flannery, John, Batten, Carrie   +8 more
openaire   +2 more sources

Cell culture adapted sheeppox virus as a challenge virus for potency testing of sheeppox vaccine.

Indian journal of experimental biology, 2009
Sheeppox virus from an outbreak of sheeppox that occurred in Srinagar (Jammu and Kashmir, India) in 2000 was isolated by inoculation of susceptible sheep and further re-isolated in cell culture. The field virus, adapted to grow in lamb testes culture, was evaluated for its potential use as challenge virus in potency testing of sheeppox vaccine ...
M, Hosamani, V, Bhanuprakash, D J, Kallesh, V, Balamurugan, A, Pande, R K, Singh   +5 more
openaire   +1 more source

Selection of a suitable viral DNA extraction method for Sheeppox virus in cell culture

Romanian Biotechnological Letters, 2021
A suitable method for the extraction of nucleic acids should be efficient, sensitive, rapid and simple. Moreover, ideally, good method should yield pure nucleic acid-free from any contaminant inhibitors. Several methods have been reported for viral deoxyribonucleic acid (DNA) isolation but limited information is available on quick and simple isolation ...
PIYALI MONDAL, C L PATEL, RACHNA SAGAR, INSHA ZAFIR, JOYSHIKH SONOWAL, KAPIL DEV, KRISHNA BHARALI, NEHA SINGH, BARKATHULLAH N, AMITESH DUBEY, BP MISHRA, BINA MISHRA   +11 more
openaire   +1 more source

Development of membrane protein‐based vaccine against lumpy skin disease virus (LSDV) using immunoinformatic tools

Veterinary Medicine and Science, Volume 10, Issue 3, May 2024.
Following the retrieval of the Membrane glycoprotein of LSDV (Gene Bank ID: QIN91553.1), it was subjected to analysis for B‐ and T‐cell epitopes and other parameters. Subsequently, the construct for the 3D structure of the vaccine chimera was generated.
Md. Salauddin, Mohammad Enamul Hoque Kayesh, Md. Suruj Ahammed, Sukumar Saha, Md. Golzar Hossain   +4 more
wiley   +1 more source

Outbreak Investigation, Isolation, and Molecular Characterization of Lumpy Skin Disease Virus in Cattle from North West Oromia Region, Ethiopia

Veterinary Medicine International, Volume 2024, Issue 1, 2024.
Lumpy skin disease (LSD) is an economically significant viral disease because of its high morbidity and high production loss. Vaccination of cattle using LSD vaccines is a more effective disease preventive and control strategy in endemic countries such as Ethiopia. Despite high vaccination coverage, there is an increasing number of field reports of the
Workisa Chala, Kasaye Adamu, Hawa Mohammed, Getaw Deresse, Shimelis Tesfaye, Esayas Gelaye, Carlos Viegas   +6 more
wiley   +1 more source