Results 21 to 30 of about 720 (109)

a Minor Fraction of Molecules Retains the Decoy Epitope, a Presumed Molecular Cause for Viral Persistence [PDF]

, 2013
Porcine reproductive and respiratory syndrome virus (PRRSV) is the major pathogen in the pig industry. Variability of the antigens and persistence are the biggest challenges for successful control and elimination of the disease.
Krause, Eberhard, Sinhadri, Balaji Chandrasekhar, Thaa, Bastian, Tielesch, Claudia, Veit, Michael   +4 more
core   +7 more sources

Cell Proteins Bind to A 67 Nucleotide Sequence within the 3’ Noncoding Region (NCR) of Simian Hemorrhagic Fever Virus (SFV) Negative-Strand RNA [PDF]

, 1998
The 3'NCR of the SHFV negative-strand RNA [SHFV 3'(-)NCR RNA] is thought to be the initiation site of full-length and possibly also subgenomic positive-strand RNA and so is likely to contain cis-acting signals for viral RNA replication. Cellular and viral proteins may specifically interact with this region to form replication complexes.
Y K, Hwang, M A, Brinton
openaire   +2 more sources

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V., Meulenberg, J.J.M., Rottier, P.J.M., Verheije, M.H.   +3 more
core   +2 more sources

Equine Arteritis Virus Does Not Induce Interferon Production in Equine Endothelial Cells: Identification of Nonstructural Protein 1 as a Main Interferon Antagonist

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The objective of this study was to investigate the effect of equine arteritis virus (EAV) on type I interferon (IFN) production. Equine endothelial cells (EECs) were infected with the virulent Bucyrus strain (VBS) of EAV and expression of IFN‐β was measured at mRNA and protein levels by quantitative real‐time RT‐PCR and IFN bioassay using vesicular ...
Yun Young Go, Yanhua Li, Zhenhai Chen, Mingyuan Han, Dongwan Yoo, Ying Fang, Udeni B. R. Balasuriya, Denis Archambault   +7 more
wiley   +1 more source

Zoonotic potential of simian arteriviruses [PDF]

, 2015
Wild nonhuman primates are immediate sources and long-term reservoirs of human pathogens. However, ethical and technical challenges have hampered the identification of novel blood-borne pathogens in these animals.
Apetrei, Cristian, Bailey, Adam L, Freimer, Nelson B, Friedrich, Thomas C, Goldberg, Tony L, Jasinska, Anna J, Jolly, Clifford J, Kuhn, Jens H, Lauck, Michael, Marx, Preston A, O\u27Connor, David H, Phillips-Conroy, Jane E, Rogers, Jeffrey, Sibley, Samuel D   +13 more
core   +2 more sources

Genetic Diversity Analysis of Genotype 2 Porcine Reproductive and Respiratory Syndrome Viruses Emerging in Recent Years in China

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Porcine reproductive and respiratory syndrome virus (PRRSV) is characterized by its extensive genetic diversity. Here we analyzed 101 sequences of NSP2 hypervariable region, 123 ORF3 sequences, and 118 ORF5 sequences from 128 PRRSV‐positive clinical samples collected in different areas of China during 2008–early 2012.
Lei Zhou, Xiaorong Yang, Yuan Tian, Shuoyan Yin, Gang Geng, Xinna Ge, Xin Guo, Hanchun Yang, Raymond Rowland   +8 more
wiley   +1 more source

A Genome‐Wide Analysis of RNA Pseudoknots That Stimulate Efficient −1 Ribosomal Frameshifting or Readthrough in Animal Viruses

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
Programmed −1 ribosomal frameshifting (PRF) and stop codon readthrough are two translational recoding mechanisms utilized by some RNA viruses to express their structural and enzymatic proteins at a defined ratio. Efficient recoding usually requires an RNA pseudoknot located several nucleotides downstream from the recoding site.
Xiaolan Huang, Qiang Cheng, Zhihua Du, Marcelo A. Soares   +3 more
wiley   +1 more source

Serological survey for equine viral arteritis in several municipalities in the Orinoquia region of Colombia [PDF]

, 2014
Objective. The goal of this study was to determine the current status of the Equine Arteritis virus (EAV) in horse populations in the Orinoquia region of Colombia. Materials and methods.
Agustín Góngora O., Karl Ciuoderis A., María Barrandeguy   +2 more
core   +3 more sources

Immunological Features of the Non-Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus [PDF]

, 2015
Porcine reproductive and respiratory syndrome virus (PRRSV) is currently one of the most important viruses affecting the swine industry worldwide. Despite the large number of papers published each year, the participation of non-structural proteins (nsps)
Burgara Estrella, Alexel, Hernández, Jesús, Mateu de Antonio, Enrique María, Rascón Castelo, Edgar   +3 more
core   +4 more sources

Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei [PDF]

, 2016
TbPARG in Trypanosoma brucei. A) TbPARG localization in untreated (control) and in procyclic cultures exposed to 500 μM H2O2 for 10 min. IFI was carried out as reported in our previous work [33].
Harikanth Venkannagari, Lari Lehtiö, Mariana Schlesinger, Mirtha M. Flawiá, Mohit Narwal, Salomé C. Vilchez Larrea, Silvia H. Fernández Villamil, Teemu Haikarainen   +7 more
core   +6 more sources