Results 41 to 50 of about 1,593,019 (236)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An Approach to Multidimensional Discrete Generating Series
MathematicsWe extend existing functional relationships for the discrete generating series associated with a single-variable linear polynomial coefficient difference equation to the multivariable case.
Svetlana S. Akhtamova +2 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Écrits de relève de poste : une activité continue
Activités, 2013 Shift changeover periods, when one team relieves another, contribute to achieving the continuity and reliability of shift work. This article considers first-line supervisory staff shift changeovers to be an ongoing activity carried out across successive ...
Valérie Le Bris, Béatrice Barthe
doaj +1 more source
Beurling-Type Theorem for a Class of Reproducing Kernel Hilbert Spaces
Journal of Mathematics, 2022 In this paper, it is proved that the Beurling-type theorem holds for the shift operator on a class of reproducing analytic Hilbert spaces.
Zhi-jie Wang +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Mathematical analysis of synthetic meters based on radar charts
Mathematical Modelling and Analysis, 2020 This work contains a description of a technique for constructing two synthetic indicators (measures) using a graphical presentation in the form of radar maps.
Boleslaw Borkowski +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source