Results 71 to 80 of about 541,953 (330)

The Regge limit of AdS3 holographic correlators with heavy states: towards the black hole regime

open access: yesJournal of High Energy Physics, 2021
We examine the Regge limit of holographic 4-point correlation functions in AdS3 × S 3 involving two heavy and two light operators. In this kinematic regime such correlators can be reconstructed from the bulk phase shift accumulated by the light probe as ...
Nejc Čeplak, Marcel R. R. Hughes
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Bulk phase shift, CFT Regge limit and Einstein gravity

open access: yesJournal of High Energy Physics, 2018
The bulk phase shift, related to a CFT four-point function, describes two-to-two scattering at fixed impact parameter in the dual AdS spacetime. We describe its properties for a generic CFT and then focus on large N CFTs with classical bulk duals.
Manuela Kulaxizi   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

U-operators [PDF]

open access: yes, 2005
Inspired by a statement of W. Luh asserting the existence of entire functions having together with all their derivatives and antiderivatives some kind of additive universality or multiplicative universality on certain compact subsets of the complex ...
Bernal González, Luis   +1 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

INDEX COMPUTATION OF SOME BISINGULAR OPERATORS WITH SHIFT BY HOMOTOPY METHOD

open access: yesВестник Донского государственного технического университета, 2018
The work continues to research the insufficiently explored problem of bisingular operators with shift index. It considers new cases of index computation of the bisingular operators with indisintegrative involutive shift by the homotopy method.
S. V. EFIMOV
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

INDEX COMPUTATION OF SOME BISINGULAR OPERATORS WITH SHIFT BY HOMOTOPY METHOD

open access: yesAdvanced Engineering Research, 2010
The work continues to research the insufficiently explored problem of bisingular operators with shift index. It considers new cases of index computation of the bisingular operators with indisintegrative involutive shift by the homotopy method.
S. V. EFIMOV
doaj  

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