Results 61 to 70 of about 56,619 (260)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On a clock-controlled keystream generator and its cryptographic properties
Tongxin xuebao, 2007 A new clock-controlled keystream generator was proposed,which was composed of three shift registers: two clock-controlled linear feedback shift registers A,B,and one clock-controlling nonlinear feedback shift register C.Let l1,l2 and l3 denote the length
MA Wei-ju1, FENG Deng-guo1
doaj +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Quantum LFSR Structure for Random Number Generation Using QCA Multilayered Shift Register for Cryptographic Purposes. [PDF]
Sensors (Basel), 2022 Kim HI, Jeon JC.
europepmc +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Novel parallel inputs shift registers with set/reset terminals in QCA nanotechnology
HeliyonThis paper was focused on logic gates, D-latch, parallel-parallel shift-registers, and parallel-series shift registers, which are used as basic circuits in numerous circuits as well as computational and comparative units.
Mohammad Gholami +2 more
doaj +1 more source
A Pseudorandom Binary Generator Based on Chaotic Linear Feedback Shift Register [PDF]
Iraqi Journal for Electrical and Electronic Engineering, 2016 This paper presents a simple method for the design of Chaotic Linear Feedback Shift Register (CLFSR) system. The proposed method is based on a combination of two known systems.
Saad Muhi Falih
doaj