Results 111 to 120 of about 1,432,960 (308)

Shift work, quality of life and work ability among Croatian hospital nurses [Smjenski rad, kvaliteta života i radna sposobnost kod medicinskih sestara u Hrvatskim bolnicama]

, 2013
This paper is a report of a study of the associations of shift work with work ability and quality of life (QoL) among clinical nurses. A cross-sectional study was conducted in 2007-2008 on 1124 nurses using the Work Ability Index Questionnaire and the ...
Juras, Karin, Milošević, Milan, Mustajbegović, Jadranka, Golubić, Rajna, Sorić, Maša   +4 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Peak Shift in Remembering

, 2003
If remembering is discriminative behaviour along the dimension of time and if, as Sargisson and White (2001) argued, generalisation around a peak can occur in this behaviour, then the peak shift which has been shown in discrimination along so many other ...
Hoan, Andros
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

When owls struggle at work: chronotype, burnout, and work ability in shift and non-shift employees

BMC Psychology
Evening chronotype has been linked to poorer occupational functioning, yet the mechanisms through which circadian preference relates to work ability remain insufficiently understood.
Łukasz Baka, Łukasz Kapica, Szymon Warszawski, Andrzej Najmiec, Joanna Bugajska   +4 more
doaj   +1 more source

Mortality of Shift Workers

Scandinavian Journal of Work, Environment & Health, 2017
Is shift work associated with higher mortality risk? That question has been the subject of much discussion for decades. Mortality risk includes concerns that reflect not only incidence but also case fatality, treatment, information of death certificates,
Anders Knutsson
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Split-shift work in relation to stress, health and psychosocial work factors among bus drivers

, 2017
BACKGROUND: Shift work has been associated with poor health, sleep and fatigue problems and low satisfaction with working hours. However, one type of shift working, namely split shifts, have received little attention.OBJECTIVE: This study examined stress,
Anna Anund, Ihlström, Jonas,, Ihlström, Jonas, Jonas Ihlström, Anund, Anna,, Kecklund, Göran,, Anund, Anna, Göran Kecklund   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Breast cancer among shift workers: results of the WOLF longitudinal cohort study

, 2013
Objective The aim of this study was to investigate whether shift work (with or without night work) is associated with increased risk of breast cancer. Methods The population consisted of 4036 women.
Karlsson, Berndt, Westerlund, Hugo,, Alfredsson, L,, Fransson, Eleonor I, Knutsson, Anders, Westerlund, H, Karlsson, Berndt,, Knutsson, Anders,, Fransson, E,, Åkerstedt, T, Åkerstedt, T,, Fransson, Eleonor I., Fransson, E, Westerholm, Peter, Westerholm, P, Westerholm, Peter,, Westerlund, H,, Karlsson, B,, Åkerstedt, Torbjörn, Westerholm, P,, Åkerstedt, Torbjörn,, Karlsson, B, Alfredsson, Lars, Alfredsson, L, Westerlund, Hugo, Fransson, Eleonor,   +25 more
core   +1 more source