Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
RESPONSE: Re: Night Shift Work, Light at Night, and Risk of Breast Cancer [PDF]
, 2002 Johnni Hansen
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Association Between Shift Work and Auditory-Cognitive Processing in Middle-Aged Healthcare Workers. [PDF]
Audiol ResRoque M, Marques T, Serrano M.
europepmc +1 more source
The relationship between shift work and sleep patterns in nurses [PDF]
, 2013 Milva Maria Figueiredo De Martino +3 more
openalex +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Association of shift work with metabolic dysfunction-associated fatty liver disease among subway workers. [PDF]
Front Public HealthPeng R, Shi B, Liu J, He Z.
europepmc +1 more source
Shift Work and Poor Mental Health: A Meta-Analysis of Longitudinal Studies
, 2019 Luciana Torquati +4 more
openalex +2 more sources
Self-reported Drowsiness and Safety Outcomes While Driving After an Extended Duration Work Shift in Trainee Physicians [PDF]
, 2017 Clare Anderson +5 more
openalex +1 more source
Sickness absenteeism, work performance, and healthcare use due to respiratory infections for shift and non-shift workers [PDF]
, 2020 Marit Middeldorp +4 more
openalex +1 more source