Results 201 to 210 of about 4,685,864 (234)

Shiga-Like Toxins as Targeted Anticancer Agents

2002
A large number of structurally related protein toxins are derived from bacterial and plant sources. They target specific cell types by virtue of their receptor-binding domains that typically recognize glycolipids or glycoproteins. Some of these toxins, such as ricin and abrin, are ribosome-inactivating proteins (or RIPs) defining them as cytotoxic ...
Paul LaPointe, Jean Gariépy
openaire   +1 more source

The role of the ribosomal stalk in the activity of ricin, Shiga-like toxin 1 and Shiga-like toxin 2 in Saccharomyces cerevisiae

2011
Ricin, Shiga-like toxin 1 (Stx1) and Shiga-like toxin 2 (Stx2) are ribosome inactivating proteins (RIPs) that catalytically remove an adenine residue from the highly conserved α-sarcin/ricin loop (SRL) in the large ribosomal subunit, inhibiting the translocation step of protein synthesis.
openaire   +1 more source

Mode of Action of Shiga and Shiga-Like Toxins

1990
Enterohemorrhagic Escherichia coli 0157:H7 and other serotypes produce at least two distinct cytotoxins that affect Vero cells (Vero toxins).9,14,15,17 Both Vero toxins have been purified to homogeneity and the properties of the purified toxins have been examined extensively.9,17 One of them was found to be identical to Shiga toxin in molecular ...
openaire   +1 more source

Shiga-like toxins of enterohemorrhagic

Toxicon, 1996
E. coli, A.D. O'Brien
openaire   +1 more source

Shiga‐like toxin I is a polynucleotide:adenosine glycosidase

Molecular Microbiology, 1998
L, Barbieri, P, Valbonesi, M, Brigotti, L, Montanaro, F, Stirpe, S, Sperti   +5 more
openaire   +2 more sources

Purification and some properties of Shiga-like toxin from 0157:H7 that is immunologically identical to Shiga toxin

Microbial Pathogenesis, 1987
Takashi Yutsudo, Masatoshi Noda, Toshiya Hirayama   +2 more
exaly  

Structure-function analyses of Shiga toxin and the Shiga-like toxins

Microbial Pathogenesis, 1990
openaire   +2 more sources

Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages fromEscherichia coli933

FEMS Microbiology Letters, 1987
Randall K Holmes
exaly  

Identity of molecular structure of Shiga-like toxin I (VT1) from O157 : H7 with that of Shiga toxin

Microbial Pathogenesis, 1988
Toshifumi Takao, Chihiro Sasakawa, Yeong-Man Hong   +2 more
exaly  

Reproduction of Edema Disease of Swine with Purified Shiga-like Toxin-II Variant

Veterinary Pathology, 1991
B P Wilcock, C L Gyles
exaly