Results 111 to 120 of about 335,942 (340)

Transglutaminase‐mediated cytokeratin modifications implicated in bile‐acid‐induced hepatocyte death

The FEBS Journal, EarlyView.
Cholestasis and bile‐acid exposure enhance expression and activity of protein crosslinking enzymes TG1 and TG2 in hepatocytes. Substrate proteins were identified by mass spectrometry using biotin‐labeled peptides (pepK5/pepT26) or amine donor (biotinylated pentylamine; BPA). Crosslinking‐induced aggregation and fragmentation of keratin 18 and 8 (K18/K8)
Hideki Tatsukawa, Haruka Nakagawa, Chin Mun Yee, Keiko Kuwata, Kiyotaka Hitomi   +4 more
wiley   +1 more source

Characterization of Shigella dysenteriae 1 (Shiga) toxin purified by anti-Shiga toxin affinity chromatography [PDF]

Infection and Immunity, 1980
Shigella dysenteriae 1 (Shiga) toxin was purified from whole-cell lysates by antitoxin affinity column chromatography, radioiodination, and Sephacryl S-200 gel filtration of 125I-labeled affinity column eluates. Two chromatographic peaks were observed. The percentage of radioactivity in peak I samples immunoprecipitated with antitoxin ranged from 95 to
A D, O'Brien, G D, LaVeck, D E, Griffin, M R, Thompson   +3 more
openaire   +2 more sources

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Practical Review on Aetio-Pathogenesis and Symptoms in Pigs Affected by Clinical and Subclinical Oedema Disease and the Use of Commercial Vaccines Under Field Conditions

Animals
The impact of Oedema Disease produced by Shiga toxigenic Escherichia coli (STEC) in swine is increasing in some production countries due to increasing limitations on treatment with antimicrobials and zinc oxide, either because of the increased prevalence
Juan Hernandez-Garcia, Isaac Ballarà Rodriguez, Ramon Jordà Casadevall, Sergi Bruguera, David Llopart, Emili Barba-Vidal   +5 more
doaj   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

International Journal of Cancer, Volume 158, Issue 4, Page 994-1007, 15 February 2026.
What's new? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu, Annika Lauk, David Sedloev, Josephine Brysting, Ela Cetin, Chunan Liu, Maximilian Mönnig, Thomas Luft, Haiyang Yun, Michael Schmitt, Tim Sauer, Fengbiao Zhou, Christian Rohde, Carsten Müller‐Tidow   +13 more
wiley   +1 more source

Escherichia Species Diversity Across Pristine and Impacted Catchments: Evidence for Avian Sources of Escherichia marmotae in Aotearoa/New Zealand

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Escherichia spp. were obtained from pristine and impacted environments to define community structure and assess potential human health risks. E. coli was more prevalent from sites affected by livestock or human activities, whereas non‐E. coli Escherichia spp. were more prevalent in avian faeces and native forest with fewer faecal sources.
Adrian L. Cookson, Marie Moinet, Jonathan C. Marshall, Patrick J. Biggs, Lynn E. Rogers, Rose M. Collis, Megan Devane, Rebecca Stott, Richard Muirhead   +8 more
wiley   +1 more source

Microangiopathic Anemia without Thrombocytopenia and Kidney Disease in a Child with Diarrhea Caused by Shiga Toxin-Producing Escherichia coli [PDF]

, 2017
A child with a history of diarrhea presented with transient anemia, reticolucytosis, and red blood cell fragmentation. Blood pressure and levels of blood platelets, creatinine, and urea were normal, as were results of urinalysis.
Bianchetti, Mario G., Meier, Paul W., Pachlopnik, Jana M., Rudin, Christoph, von der Weid, Nicolas X.   +4 more
core  

Diagnostics of dairy and beef cattle diarrhea. [PDF]

, 2012
Calf diarrhea is a multifactorial disease related to a combination of host and pathogen factors. The most common pathogens found in diarrheic calves are cryptosporidium, rotavirus, coronavirus, Salmonella, attaching and effacing E coli and F5 (K99 ...
Blanchard, Patricia Carey
core   +1 more source

Ischemic Stroke in Hypereosinophilic Syndrome: A Clinicopathologic Study of Two Cases

Neuropathology, Volume 46, Issue 1, February 2026.
ABSTRACT Ischemic stroke is a rare complication of hypereosinophilic syndrome (HES). Manifestations of stroke in HES have been described in the radiologic literature; however the pathologic characterization of central nervous system (CNS) involvement in HES is limited.
Karina C. Martin, Dan Straathof, Chi Lai, Harry V. Vinters   +3 more
wiley   +1 more source