Results 111 to 120 of about 54,271 (248)

Genetic diversity and pathogenic potential of Shiga toxin-producing Escherichia coli (STEC) derived from German flour

, 2021
Michaela Projahn, Marina C. Lamparter, Petra Ganas, André Goehler, Sandra C. Lorenz-Wright, Dietrich Maede, Angelika Fruth, Christina Lang, Elisabeth Schuh   +8 more
openalex   +1 more source

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, Volume 45, Issue 12, Page 2641-2653, December 2025.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

Emerging Infectious Diseases, 2014
Shiga toxins (Stx) are cytotoxins involved in severe human intestinal disease. These toxins are commonly found in Shigella dysenteriae serotype 1 and Shiga-toxin–producing Escherichia coli; however, the toxin genes have been found in other Shigella ...
Miranda D. Gray, Keith A. Lampel, Nancy A. Strockbine, Reinaldo E. Fernandez, Angela R. Melton-Celsa, Anthony T. Maurelli   +5 more
doaj   +1 more source

Modular Nanosensing Platforms for Tuberculosis and Beyond: Engineering Biomaterials Toward Cross‐Pathogen Diagnostic Universality

MedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li, Yuxin Luo, Wenqiang Li, Yiqing Wang, Yunze Tai, Zhiping Deng, Yao Luo   +6 more
wiley   +1 more source

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

Cell Reports, 2018
Summary: The non-canonical caspase-4 and canonical NLRP3 inflammasomes are both activated by intracellular lipopolysaccharide (LPS), but the crosstalk between these two pathways remains unclear.
Jaye M. Platnich, Hyunjae Chung, Arthur Lau, Christina F. Sandall, Adom Bondzi-Simpson, Huey-Miin Chen, Takanori Komada, Aaron C. Trotman-Grant, Jeremy R. Brandelli, Justin Chun, Paul L. Beck, Dana J. Philpott, Stephen E. Girardin, May Ho, Roger P. Johnson, Justin A. MacDonald, Glen D. Armstrong, Daniel A. Muruve   +17 more
doaj   +1 more source

Consensus report: E. coli O104:H4 (HUSEC041) and the potential threat to European water supplies. [PDF]

, 2011
Among the 3rd Seminar for PhD students working on Water and Health which was held in Cannes on 27–29 June 2011, experts from a number of universities and research institutes took the opportunity to discuss the emergence of Escherichia coli O104:H4 in ...
Exner, Martin, Hartemann, Philippe, Hunter, Paul R, Levi, Yves, Loret, Jean-Francois, Mathys, Werner, Villesot, Daniel, Wilhelm, Michael   +7 more
core  

Comparison of Droplet Digital PCR and qPCR for the Quantification of Shiga Toxin-Producing Escherichia coli in Bovine Feces [PDF]

, 2016
Bavo Verhaegen, Koen De Reu, Lieven De Zutter, Karen Verstraete, Marc Heyndrickx, Els Van Coillie   +5 more
openalex   +1 more source

Diarrheagenic and ESBL Potential of Escherichia coli From Publicly Shared Common Touch Surfaces

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Frequently touched surfaces (FTS) in public areas play a critical role in the transmission of infectious pathogens, including drug‐resistant bacteria. In this study, we identified multidrug‐resistant, ESBL‐producing diarrheagenic Escherichia coli on FTS.
Mohammad Arif, Asma Ul Hosna, Ishrat Jahan, Md. Ashiquen Nobi, Most. Shumi Akhter Shathi, MD. Nazmul Hasan, Jayedul Hassan, S. M. Lutful Kabir   +7 more
wiley   +1 more source

Safety evaluation of the food enzyme triacylglycerol lipase from the pregastric tissues of calves, kids and lambs

EFSA Journal, Volume 23, Issue 11, November 2025.
Abstract The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is prepared from the pregastric tissues of calves, kids and lambs by DSM Food Specialties B.V. No issue of concern was identified from the food enzyme manufacturing process. The food enzyme is intended to be used in two food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Magdalena Andryszkiewicz, Daniele Cavanna, Yi Liu   +15 more
wiley   +2 more sources

A Murine Model of Shigellosis: Pathophysiology of Shiga Toxin-2 Secreting Citrobacter Rodentium [PDF]

, 2019
Graduate ...
Thompson, Hannah
core   +1 more source