Identification of the long polar fimbriae gene variants in the locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli strains isolated from humans and cattle in Argentina [PDF]
, 2010 The long polar fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. Studies have demonstrated the presence of lpf genes in several pathogenic E.
Galli, Lucía +2 more
core +2 more sources
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells.
PLoS ONE, 2015 The heat shock protein 90 (Hsp90) inhibitor geldanamycin (GA) has been shown to alter endosomal sorting, diverting cargo destined for the recycling pathway into the lysosomal pathway. Here we investigated whether GA also affects the sorting of cargo into
Anne Berit Dyve Lingelem +4 more
doaj +1 more source
Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking [PDF]
, 2010 The oxidative cyclisation of a range of benzothieno[2,3-d]pyrimidine hydrazones (7a–j) to the 1,2,4-triazolo[4,3-c]pyrimidines (8a–j) catalysed by lithium iodide or to the 1,2,4-triazolo[1,5-c]pyrimidines (10a–j) with sodium carbonate is presented.
Ahmed +46 more
core +1 more source
Escherichia coli strains producing a novel Shiga toxin 2 subtype circulate in China.
International Journal of Medical Microbiology, 2019 Shiga toxin (Stx) is the key virulence factor in Shiga toxin producing Escherichia coli (STEC), which can cause diarrhea and hemorrhagic colitis with life-threatening complications. Stx comprises two toxin types, Stx1 and Stx2. Several Stx1/Stx2 subtypes
Xi Yang +9 more
semanticscholar +1 more source
Global and regional source attribution of Shiga toxin-producing Escherichia coli infections using analysis of outbreak surveillance data [PDF]
, 2019 Shiga toxin-producing Escherichia coli (STEC) infections pose a substantial health and economic burden worldwide. To target interventions to prevent foodborne infections, it is important to determine the types of foods leading to illness.
Devleesschauwer, Brecht +3 more
core +2 more sources
Archives of Veterinary Medicine, 2020 Shiga-toxin-producing Escherichia coli (STEC) and Salmonella enterica serovar Typhimurium (STDT104) are foodborne pathogens of public health significance.
Maja Velhner +6 more
doaj +1 more source
Draft genome sequences of Escherichia coli O157: H7 strains Rafaela_II (clade 8) and 7.1_Anguil (clade 6) from cattle in Argentina [PDF]
, 2015 Escherichia coli O157:H7 is a major etiologic agent of diseases in humans that cause diarrhea, hemorrhagic colitis, and hemolytic-uremic syndrome. Here, we report the draft genome sequences of two strains isolated from cattle that had high levels of ...
Amadio, Ariel Fernando +4 more
core +1 more source
Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease
Toxins, 2010 Shiga toxin-producing Escherichia coli is a contaminant of food and water that in humans causes a diarrheal prodrome followed by more severe disease of the kidneys and an array of symptoms of the central nervous system.
Tom G. Obrig
doaj +1 more source
Topological data analysis of Escherichia coli O157:H7 and non-O157 survival in soils. [PDF]
, 2014 Shiga toxin-producing E. coli O157:H7 and non-O157 have been implicated in many foodborne illnesses caused by the consumption of contaminated fresh produce.
Crowley, David E +6 more
core +2 more sources
Annals of Biostatistics & Biometric Applications, 2019 Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, expressed by genes considered to be part of the genome of lambdoid prophages.
A. Heidari
semanticscholar +1 more source