Results 61 to 70 of about 19,735 (216)

Enterohemorrhagic Escherichia coli with particular attention to the German outbreak strain O104:H4 [PDF]

, 2012
This review deals with the epidemiology and ecology of enterohemorrhagic Escherichia coli (EHEC), a subset of the verocytotoxigenic Escherichia coli (VTEC), and subsequently discusses its public health concern.
De Reu, K, De Zutter, Lieven, Joris, Adelheid, Vanrompay, Daisy, Verstraete, K   +4 more
core   +1 more source

Microarray-based screening of differentially expressed genes of E. coli O157:H7 Sakai during preharvest survival on butterhead lettuce [PDF]

, 2016
Numerous outbreaks of Escherichia coli O157:H7 have been linked to the consumption of leafy vegetables. However, up to the present, little has been known about E.
Cottyn, Bart, Heyndrickx, Marc, Holden, Nicola, Maes, Martine, Uyttendaele, Mieke, Van der Linden, Inge, Vlaemynck, Geertrui   +6 more
core   +3 more sources

Shiga toxin binds to activated platelets [PDF]

Journal of Thrombosis and Haemostasis, 2004
Hemolytic uremic syndrome (HUS) is associated with acute renal failure in children and can be caused by Shiga toxin (Stx)-producing Escherichia coli. Thrombocytopenia and formation of renal thrombi are characteristic of HUS, suggesting that platelet activation is involved in its pathogenesis. However, whether Shiga toxin directly activates platelets is
S A, Ghosh, R K, Polanowska-Grabowska, J, Fujii, T, Obrig, A R L, Gear   +4 more
openaire   +2 more sources

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Identification and detection of iha subtypes in LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains isolated from humans, cattle and food [PDF]

, 2019
LEE-negative Shiga toxin-producing Escherichia coli (STEC) strains are important cause of infection in humans and they should be included in the public health surveillance systems.
Colello, Rocío, Del Canto, Felipe, Etcheverría, Analía Inés, Krüger, Alejandra, Padola, Nora Lía, Velez, María Victoria, Vidal, Roberto   +6 more
core   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Diarrheagenic toxins in stool correlate to drinking water from improved water sources in Ethiopia

Environmental Challenges, 2022
Escherichia coli toxins are the most common types found in association with disease in E. coli bacteria. They are found in nearly all pathogenic E. coli bacteria either released from the bacteria or E. coli cell or both transmitted via the orofecal route.
Shibabaw Tadesse Gemeda, Adey Feleke Desta, Sirak Robele Gari, Jana Jass, Dessalegn Abeje Tefera   +4 more
doaj   +1 more source

Applying phylogenomics to understand the emergence of Shiga Toxin producing Escherichia coli O157:H7 strains causing severe human disease in the United Kingdom [PDF]

, 2015
Shiga Toxin producing Escherichia coli (STEC) O157:H7 is a recently emerged zoonotic pathogen with considerable morbidity. Since the serotype emerged in the 1980s, research has focussed on unravelling the evolutionary events from the E.
Allison, Lesley, Ashton, Philip M., Byrne, Lisa, Chase-Topping, Margo E., Dallman, Timothy J., Ellis, Richard, Gally, David L., Grant, Kathie A., Gunn, George G., Hanson, Mary, Holmes, Anne, Jenkins, Claire, Perry, Neil T., Petrovska, Liljana, Wain, John, Woolhouse, Mark E.J.   +15 more
core   +2 more sources

Survival Outcomes of Gemcitabine–Cisplatin–S‐1 Versus Gemcitabine–Cisplatin in Unresectable Biliary Tract Cancer: A Multicenter Retrospective Study With a Focus on Conversion Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this multicenter retrospective study conducted by the Biliary Tract Club, we compared survival outcomes between gemcitabine–cisplatin–S‐1 (GCS) and gemcitabine–cisplatin (GC) in patients with unresectable biliary tract cancer, with a particular focus on conversion surgery. GCS was associated with longer overall and progression‐free survival compared
Hisashi Kosaka, Masahiko Kinoshita, Satoshi Yasuda, Satoru Kakizaki, Rie Sugimoto, Jun Sakata, Kiyonori Yamai, Takeshi Hatanaka, Yusuke Yamamoto, Toshifumi Sato, Toru Ishikawa, Takanori Morikawa, Jun Hanaoka, Haruki Mori, Hidenori Toyoda, Tsuyoshi Sanuki, Misaki Yokoi, Hiroyuki Shibata, Koji Fukuda, Kazuhito Kawata, Koji Amaya, Takashi Ito, Masaaki Hidaka, Atsushi Naganuma, Keishi Sugimachi, Satoshi Toshiyama, Makoto Yamasaki, Masaki Kaibori   +27 more
wiley   +1 more source

Occurrence of Escherichia coli virulence genes in feces of wild birds from Central Italy

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To investigate the potential role of wild birds as fecal spreaders of enteropathogenic, enterohemorrhagic and Shiga-toxins producing Escherichia coli (E. coli), enteropathogenic E. coli, enterohemorrhagic E.
Fabrizio Bertelloni, Errica Lunardo, Guido Rocchigiani, Renato Ceccherelli, Valentina Viginia Ebani   +4 more
doaj   +1 more source