Results 41 to 50 of about 130,160 (165)

Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]

, 2011
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nejman, Bożena, Nadratowska-Wesołowska, Beata, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Szalewska-Pałasz, Agnieszka   +4 more
core   +1 more source

Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]

, 2007
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Falguières, Thomas, Roberts, L., Smith, Daniel C., Lord, J., Fradagrada, Alexandre, Amessou, Mohamed, Amessou, M., Johannes, Ludger, Fradagrada, A., Falguieres, T., Lord, Mike, Roberts, L. M. (Lynne M.), Lamaze, Christophe, Lamaze, C., Johannes, L., Smith, D.   +15 more
core   +1 more source

Prevalence and genetic characterization of shiga toxin-producing Escherichia coli isolates from slaughtered animals in Bangladesh [PDF]

, 2008
To determine the prevalence of Shiga toxin (Stx)-producing Escherichia coli (STEC) in slaughter animals in Dhaka, Bangladesh, we collected rectal contents immediately after animals were slaughtered.
Beumer, R.R., Boer, E., de, de Boer, E., Islam, M.A., Talukder, K.A., Zwietering, M.H., Mondol, A.S., Heuvelink, A.E.   +7 more
core   +1 more source

Molecular Characterization of Shiga Toxin Produced by Escherichia coli Isolated from Milk Samples in Baghdad City

Journal of Pure and Applied Microbiology, 2022
Raw milk is a nutrient-rich food that is considered a high-quality nutritional medium for many microorganism, including Escherichia coli. The aim of the present work was the diagnosis, by molecular methods, of Shiga toxins produced by E.
Balqees Yahya Najm, Sarab H. Khaleel, Hala Mahmmad Majeed   +2 more
doaj   +1 more source

Sequence Variability of P2-Like Prophage Genomes Carrying the Cytolethal Distending Toxin V Operon in Escherichia coli O157 [PDF]

, 2013
Cytolethal distending toxins (CDT) are potent cytotoxins of several Gram-negative pathogenic bacteria, including Escherichia coli, in which five types (CDT-I to CDT-V) have been identified so far.
Dobrindt, Ulrich, Maróti, Gergely, Sváb, Domonkos, Horváth, Balázs, Tóth, István   +4 more
core   +1 more source

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network [PDF]

, 2008
The small-molecule inhibitor Exo2 {4-hydroxy-3-methoxy-(5,6,7,8-tetrahydrol[1]benzothieno[2,3-d]pyrimidin-4-yl)hydraz-one benzaldehyde} has been reported to disrupt the Golgi apparatus completely and to stimulate Golgi–ER (endoplasmic reticulum) fusion ...
Amessou, M, Boal, Frédéric, Mohammed, Ludger, Roberts, LM, Stephens, David J, Smith, Daniel C., Clarkson, GJ, Stephens, D. J., Lord, JM, Clarkson, Guy J., Clarkson, Guy J, Roberts, Lynne M, Amessou, M., Watson, Peter D, Lord, J. M., Watson, Peter, Roberts, L. M. (Lynne M.), Amessou, Mohammed, Spooner, Robert A, Boal, F., Johannes, L., Smith, D. C., Smith, Daniel C, Clarkson, G. J., Spooner, Robert A., Stephens, David J., Watson, P, Smith, DC, Lord, J. Michael, Johannes, Ludger, Lord, Mike, Johannes, L, Spooner, RA, Boal, F, Stephens, DJ, Spooner, R. A., Watson, Peter Duncan, Roberts, L. M.   +37 more
core   +1 more source

Epithelial cell signaling responses to enterohemorrhagic Escherichia coli infection

Memorias do Instituto Oswaldo Cruz, 2005
Enterohemorrhagic Escherichia coli, including the serotype O157:H7 that is most commonly identified with human disease, cause both sporadic cases and outbreaks of non-bloody diarrhea and hemorrhagic colitis.
Peter JM Ceponis, Jason D Riff, Philip M Sherman   +2 more
doaj   +1 more source

Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

Emerging Infectious Diseases, 2014
Shiga toxins (Stx) are cytotoxins involved in severe human intestinal disease. These toxins are commonly found in Shigella dysenteriae serotype 1 and Shiga-toxin–producing Escherichia coli; however, the toxin genes have been found in other Shigella ...
Miranda D. Gray, Keith A. Lampel, Nancy A. Strockbine, Reinaldo E. Fernandez, Angela R. Melton-Celsa, Anthony T. Maurelli   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source