Results 31 to 40 of about 9,827 (181)
Active Shiga-like toxin produced by some Aeromonas spp., isolated in Mexico City
Frontiers in Microbiology, 2016 Shiga-like toxins (Stx) represent a group of bacterial toxins involved in human and animal diseases. Stx is produced by enterohemorrhagic Escherichia coli, Shigella dysenteriae type 1, Citrobacter freundii and Aeromonas spp.
Ingrid Palma-Martínez +7 more
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Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis
Life Science Alliance, 2019 This study reports an unexpected role of late endosome–lysosome fusion in early endosome-to-Golgi trafficking of Shiga toxins and identifies tamoxifen to be a potent inhibitor of Shiga toxicosis. Shiga toxin 1 (STx1) and 2 (STx2), produced by Shiga toxin–
Andrey S Selyunin +3 more
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Retrograde transport pathways utilised by viruses and protein toxins
Virology Journal, 2006 A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera
Roberts Lynne M +4 more
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Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits [PDF]
Journal of Bacteriology, 1990 The A-subunit polypeptides of Shiga toxin, the Shiga-like toxins (SLTs), and the plant lectin ricin inactivate eucaryotic ribosomes by enzymatically depurinating 28S rRNA. Comparison of the amino acid sequences of the members of the Shiga toxin family and ricin revealed two regions of significant homology that lie within a proposed active-site cleft of
M P, Jackson +2 more
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Rapid and Label-Free Immunosensing of Shiga Toxin Subtypes with Surface Plasmon Resonance Imaging
Toxins, 2020 Shiga toxin-producing Escherichia coli (STEC) are responsible for gastrointestinal diseases reported in numerous outbreaks around the world as well as in the United States. Current detection methods have limitation to implement for rapid field-deployable
Bin Wang +3 more
doaj +1 more source
PREPARATION AND PROPERTIES OF SHIGA TOXIN AND TOXOID [PDF]
Journal of Experimental Medicine, 1946 1. Shigella dysenteriae (Shiga) can, under the proper cultural conditions, produce a soluble toxin which is independent of the specific somatic polysaccharide antigen. A method is described for the rapid production of this toxin by an avirulent R variant of this organism. 2.
R J, DUBOS, J W, GEIGER
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Journal of Pure and Applied Microbiology, 2022 Raw milk is a nutrient-rich food that is considered a high-quality nutritional medium for many microorganism, including Escherichia coli. The aim of the present work was the diagnosis, by molecular methods, of Shiga toxins produced by E.
Balqees Yahya Najm +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster +13 more
wiley +2 more sources
Epithelial cell signaling responses to enterohemorrhagic Escherichia coli infection
Memorias do Instituto Oswaldo Cruz, 2005 Enterohemorrhagic Escherichia coli, including the serotype O157:H7 that is most commonly identified with human disease, cause both sporadic cases and outbreaks of non-bloody diarrhea and hemorrhagic colitis.
Peter JM Ceponis +2 more
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Emerging Infectious Diseases, 2014 Shiga toxins (Stx) are cytotoxins involved in severe human intestinal disease. These toxins are commonly found in Shigella dysenteriae serotype 1 and Shiga-toxin–producing Escherichia coli; however, the toxin genes have been found in other Shigella ...
Miranda D. Gray +5 more
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