Results 31 to 40 of about 9,721 (166)
Frontiers in Cellular and Infection Microbiology, 2012 Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagic colitis is lacking.
Samuel eStone +10 more
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Frontiers in Cellular and Infection Microbiology, 2021 Shiga toxin-producing Escherichia coli (STEC) is a global foodborne bacterial pathogen that is often accountable for colon disorder or distress. STEC commonly induces severe diarrhea in hosts but can cause critical illnesses due to the Shiga toxin ...
Su-bin Hwang +6 more
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iScience, 2022 Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways.
Yu Wu +31 more
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Detection of E. coli O157:H7 and Shigella dysenteriae toxins in clinical samples by PCR-ELISA
Brazilian Journal of Infectious Diseases, 2015 Shiga toxin producing bacteria are potential causes of serious human disease such as hemorrhagic colitis, severe inflammations of ileocolonic regions of gastrointestinal tract, thrombocytopenia, septicemia, malignant disorders in urinary ducts, hemolytic
Jafar Amani +3 more
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Active Shiga-like toxin produced by some Aeromonas spp., isolated in Mexico City
Frontiers in Microbiology, 2016 Shiga-like toxins (Stx) represent a group of bacterial toxins involved in human and animal diseases. Stx is produced by enterohemorrhagic Escherichia coli, Shigella dysenteriae type 1, Citrobacter freundii and Aeromonas spp.
Ingrid Palma-Martínez +7 more
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Tamoxifen blocks retrograde trafficking of Shiga toxin 1 and 2 and protects against lethal toxicosis
Life Science Alliance, 2019 This study reports an unexpected role of late endosome–lysosome fusion in early endosome-to-Golgi trafficking of Shiga toxins and identifies tamoxifen to be a potent inhibitor of Shiga toxicosis. Shiga toxin 1 (STx1) and 2 (STx2), produced by Shiga toxin–
Andrey S Selyunin +3 more
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Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits [PDF]
Journal of Bacteriology, 1990 The A-subunit polypeptides of Shiga toxin, the Shiga-like toxins (SLTs), and the plant lectin ricin inactivate eucaryotic ribosomes by enzymatically depurinating 28S rRNA. Comparison of the amino acid sequences of the members of the Shiga toxin family and ricin revealed two regions of significant homology that lie within a proposed active-site cleft of
M P, Jackson +2 more
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PREPARATION AND PROPERTIES OF SHIGA TOXIN AND TOXOID [PDF]
Journal of Experimental Medicine, 1946 1. Shigella dysenteriae (Shiga) can, under the proper cultural conditions, produce a soluble toxin which is independent of the specific somatic polysaccharide antigen. A method is described for the rapid production of this toxin by an avirulent R variant of this organism. 2.
R J, DUBOS, J W, GEIGER
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Retrograde transport pathways utilised by viruses and protein toxins
Virology Journal, 2006 A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we review studies on the ER trafficking cholera
Roberts Lynne M +4 more
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Rapid and Label-Free Immunosensing of Shiga Toxin Subtypes with Surface Plasmon Resonance Imaging
Toxins, 2020 Shiga toxin-producing Escherichia coli (STEC) are responsible for gastrointestinal diseases reported in numerous outbreaks around the world as well as in the United States. Current detection methods have limitation to implement for rapid field-deployable
Bin Wang +3 more
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