Hemolytic uremic syndrome related to Shiga-like toxin-producing Escherichia coli with encephalitis hiding a human herpesvirus-6 infection: a case report [PDF]
Journal of Medical Case Reports, 2021 Background Cardiac and neurological involvement in hemolytic uremic syndrome are life-threatening complications. The most frequent complications of cardiac involvement in hemolytic uremic syndrome are myocarditis and cardiac dysfunction due to fluid ...
Sophie Mounier +5 more
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Shiga-Like Toxin Produced by Local Isolates of O157:H7 Induces Apoptosis of the T47 Breast Cancer Cell Line [PDF]
Breast Cancer: Basic and Clinical Research, 2021 Purpose: It has been suggested that Shiga-like toxins produced by Escherichia coli O157:H7 could be used as novel therapeutic agents against malignant tumors. In addition, the antitumor potency of local isolates from Indonesia, which are known to be less
Komang Januartha Putra Pinatih +3 more
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Shiga and Shiga-like toxins [PDF]
Microbiological Reviews, 1987 Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
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Baicalin Inhibits the Lethality of Shiga-Like Toxin 2 in Mice [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT Shiga-like toxins (Stxs), produced by pathogenic Escherichia coli , are a major virulence factor involved in severe diseases in human and animals. These toxins are ribosome-inactivating proteins, and treatment for diseases caused by them is not available.
Jing, Dong +8 more
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Active Shiga-like toxin produced by some Aeromonas spp., isolated in Mexico City [PDF]
Frontiers in Microbiology, 2016 Shiga-like toxins (Stx) represent a group of bacterial toxins involved in human and animal diseases. Stx is produced by enterohemorrhagic Escherichia coli, Shigella dysenteriae type 1, Citrobacter freundii and Aeromonas spp.
Ingrid Palma-Martínez +7 more
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iScience, 2022 Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways.
Yu Wu +31 more
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Heterologous Expression of Shiga-Like Toxin Type 2 in Microgravity Condition [PDF]
فصلنامه علوم و فناوری فضایی, 2022 Gravity is an influential force on living organisms on earth, including microorganisms. E. coli O157: H7 causes complications such as bloody diarrhea and hemolytic uremic syndrome in humans and immunization is the main way to fight it. Subunit B of Shiga-
Maryam Salavatifar +2 more
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The pathogenic mechanisms of Shiga toxin and the Shiga‐like toxins [PDF]
Molecular Microbiology, 1991 SummaryIt is now well documented that some enteric bacteria which cause diarrhoeal and/or dysenteric disease produce, at high levels, one or more of a family of protein toxins referred to as Shiga toxin and Shiga‐like toxins (SLTs; alternatively called verocytotoxins or VTs).
V L, Tesh, A D, O'Brien
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Development of Recombinant Lactococcus lactis Displaying Albumin-Binding Domain Variants against Shiga Toxin 1 B Subunit. [PDF]
PLoS ONE, 2016 Infections with shiga toxin-producing bacteria, like enterohemorrhagic Escherichia coli and Shigella dysenteriae, represent a serious medical problem. No specific and effective treatment is available for patients with these infections, creating a need ...
Petra Zadravec +8 more
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Hybridization of Escherichia coli producing Shiga-like toxin I, Shiga-like toxin II, and a variant of Shiga-like toxin II with synthetic oligonucleotide probes [PDF]
Infection and Immunity, 1989 Synthetic oligonucleotides, constructed from the nucleotide sequences of genes coding for the A subunit of Shiga-like toxin (SLT) I and the B subunit of SLT-II, were used as probes at different degrees of stringency to identify Escherichia coli producing different types of SLTs. At 45 degrees C, the A-I oligonucleotide probe hybridized with E.
J E, Brown +4 more
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