Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagic colitis is lacking.
Samuel eStone +10 more
doaj +1 more source
Background: In 2018, a Shiga toxin–producing Escherichia coli O121 outbreak that affected seven individuals was associated with raw milk Gouda-like cheese produced in British Columbia, Canada. Objectives: To describe the E.
Eva Boyd +10 more
doaj +1 more source
Fighting Fire with Fire: Phage Potential for the Treatment of E. coli O157 Infection
Hemolytic⁻uremic syndrome is a life-threating disease most often associated with Shiga toxin-producing microorganisms like Escherichia coli (STEC), including E. coli O157:H7.
Cristina Howard-Varona +12 more
doaj +1 more source
Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p [PDF]
Background Escherichia coli Shiga-like toxin 1 normally traffics to the endoplasmic reticulum (ER) in sensitive mammalian cells from where the catalytic A chain (SLTxA1) dislocates to the cytosol to inactivate ribosomes.
Lynne M. Roberts (150050) +21 more
core +2 more sources
CHITOSAN INHIBITION TEST AGAINST E. coli AND DIGESTIBILITY OF THE RATION IN THE IN-VITRO METHOD
Diarrhea and vomiting are often caused by E coli bacteria. E coli bacteria has a strain of Shigatoxigenic Escherichia coli (STEC), producing Shiga poisons or poisons such as Shiga (verotoxin) which are harmful and pollute nature.
Eli Sahara, Sofia Sandi, Fitra Yosi
doaj +1 more source
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]
Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Evelyn Fuchs +18 more
core +1 more source
Baicalin Protects Mice from Lethal Infection by Enterohemorrhagic Escherichia coli
Shiga-like toxin-producing Escherichia coli (STEC) O157:H7 poses grave challenges to public health by its ability to cause severe colonic diseases and renal failure in both human and animals.
Yong Zhang +11 more
doaj +1 more source
Intimin, tir, and shiga toxin 1 do not influence enteropathogenic responses to shiga toxin-producing Escherichia coli in bovine ligated intestinal loops [PDF]
Shiga toxin-producing Escherchia coli (STEC) comprises a group of attaching and effacing (A/E) enteric pathogens of animals and humans. Natural and experimental infection of calves with STEC may result in acute enteritis or subclinical infection ...
Campbell, June +23 more
core +1 more source
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants [PDF]
The antigenically distinct Shiga-like toxins (SLTs) SLT-1 and SLT-II are cytotoxic for both Vero and HeLa cells and use Gal alpha 1-4Gal beta 1-4Glc beta 1-1Cer (Gb3) molecules as functional receptors. SLT-II-related variants SLT-IIvp and SLT-IIvh, produced by a porcine isolate and a human isolate, respectively, are cytotoxic for Vero but not HeLa ...
J E, Samuel +5 more
openaire +2 more sources
Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA
Immunoglobulin A (IgA) is a candidate antibody for oral passive immunization against mucosal pathogens like Shiga toxin-producing Escherichia coli (STEC).
Katsuhiro Nakanishi +14 more
doaj +1 more source

