Results 21 to 30 of about 4,685,864 (234)

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Shiga toxin producing Escherichia coli (STEC) are a major cause of food-borne illness worldwide. However, a consensus regarding the role Shiga toxins play in the onset of diarrhea and hemorrhagic colitis is lacking.
Samuel eStone   +10 more
doaj   +1 more source

Escherichia coli O121 outbreak associated with raw milk Gouda-like cheese in British Columbia, Canada, 2018

open access: yesCanada Communicable Disease Report, 2021
Background: In 2018, a Shiga toxin–producing Escherichia coli O121 outbreak that affected seven individuals was associated with raw milk Gouda-like cheese produced in British Columbia, Canada. Objectives: To describe the E.
Eva Boyd   +10 more
doaj   +1 more source

Fighting Fire with Fire: Phage Potential for the Treatment of E. coli O157 Infection

open access: yesAntibiotics, 2018
Hemolytic⁻uremic syndrome is a life-threating disease most often associated with Shiga toxin-producing microorganisms like Escherichia coli (STEC), including E. coli O157:H7.
Cristina Howard-Varona   +12 more
doaj   +1 more source

Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p [PDF]

open access: yes, 2012
Background Escherichia coli Shiga-like toxin 1 normally traffics to the endoplasmic reticulum (ER) in sensitive mammalian cells from where the catalytic A chain (SLTxA1) dislocates to the cytosol to inactivate ribosomes.
Lynne M. Roberts (150050)   +21 more
core   +2 more sources

CHITOSAN INHIBITION TEST AGAINST E. coli AND DIGESTIBILITY OF THE RATION IN THE IN-VITRO METHOD

open access: yesJurnal Pendidikan Matematika dan IPA, 2020
Diarrhea and vomiting are often caused by E coli bacteria. E coli bacteria has a strain of Shigatoxigenic Escherichia coli (STEC), producing Shiga poisons or poisons such as Shiga (verotoxin) which are harmful and pollute nature.
Eli Sahara, Sofia Sandi, Fitra Yosi
doaj   +1 more source

Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]

open access: yes, 2007
Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Evelyn Fuchs   +18 more
core   +1 more source

Baicalin Protects Mice from Lethal Infection by Enterohemorrhagic Escherichia coli

open access: yesFrontiers in Microbiology, 2017
Shiga-like toxin-producing Escherichia coli (STEC) O157:H7 poses grave challenges to public health by its ability to cause severe colonic diseases and renal failure in both human and animals.
Yong Zhang   +11 more
doaj   +1 more source

Intimin, tir, and shiga toxin 1 do not influence enteropathogenic responses to shiga toxin-producing Escherichia coli in bovine ligated intestinal loops [PDF]

open access: yes, 2002
Shiga toxin-producing Escherchia coli (STEC) comprises a group of attaching and effacing (A/E) enteric pathogens of animals and humans. Natural and experimental infection of calves with STEC may result in acute enteritis or subclinical infection ...
Campbell, June   +23 more
core   +1 more source

Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants [PDF]

open access: yesInfection and Immunity, 1990
The antigenically distinct Shiga-like toxins (SLTs) SLT-1 and SLT-II are cytotoxic for both Vero and HeLa cells and use Gal alpha 1-4Gal beta 1-4Glc beta 1-1Cer (Gb3) molecules as functional receptors. SLT-II-related variants SLT-IIvp and SLT-IIvh, produced by a porcine isolate and a human isolate, respectively, are cytotoxic for Vero but not HeLa ...
J E, Samuel   +5 more
openaire   +2 more sources

Prevention of Shiga toxin 1-caused colon injury by plant-derived recombinant IgA

open access: yesScientific Reports, 2022
Immunoglobulin A (IgA) is a candidate antibody for oral passive immunization against mucosal pathogens like Shiga toxin-producing Escherichia coli (STEC).
Katsuhiro Nakanishi   +14 more
doaj   +1 more source

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