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Molecular Biology of Escherichia coli Shiga Toxins’ Effects on Mammalian Cells [PDF]
Shiga toxins (Stxs), syn. Vero(cyto)toxins, are potent bacterial exotoxins and the principal virulence factor of enterohemorrhagic Escherichia coli (EHEC), a subset of Shiga toxin-producing E. coli (STEC).
Christian Menge
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A High-Throughput, Precipitating Colorimetric Sandwich ELISA Microarray for Shiga Toxins [PDF]
Shiga toxins 1 and 2 (Stx1 and Stx2) from Shiga toxin-producing E. coli (STEC) bacteria were simultaneously detected with a newly developed, high-throughput antibody microarray platform.
Andrew Gehring +11 more
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P1PK blood group antigens in birds: implications for veterinary blood transfusion, human and pet health [PDF]
Background The P1PK blood group system in humans, composed of three glycosphingolipid antigens, plays a significant role in transfusion medicine. These antigens are synthesized by the enzyme α1,4-galactosyltransferase, encoded by the A4GALT gene, and ...
Anna Bereznicka +9 more
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Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee +2 more
exaly +3 more sources
The Interactions of Human Neutrophils with Shiga Toxins and Related Plant Toxins: Danger or Safety?
Shiga toxins and ricin are well characterized similar toxins belonging to quite different biological kingdoms. Plant and bacteria have evolved the ability to produce these powerful toxins in parallel, while humans have evolved a defense system that ...
Maurizio Brigotti, Brigotti Maurizio
exaly +3 more sources
Detection of Shiga Toxins by Lateral Flow Assay [PDF]
Shiga toxin-producing Escherichia coli (STEC) produce shiga toxins (Stxs) that can cause human disease and death. The contamination of food products with STEC represents a food safety problem that necessitates rapid and effective detection strategies to ...
Kathryn H. Ching +5 more
doaj +2 more sources
Shiga Toxins: An Update on Host Factors and Biomedical Applications [PDF]
Songhai Tian, Hatim Thaker, Min Dong
exaly +2 more sources
Do the A Subunits Contribute to the Differences in the Toxicity of Shiga Toxin 1 and Shiga Toxin 2? [PDF]
Shiga toxin producing Escherichia coli O157:H7 (STEC) is one of the leading causes of food-poisoning around the world. Some STEC strains produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2) or variants of either toxin, which are critical for the ...
Debaleena Basu, Nilgun E. Tumer
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Objective – obtaining and characterization of hybrid cell lines producing monoclonal antibodies against I and II types of shiga-like toxins.Materials and methods.
G. V. Kuklina +6 more
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Shiga and Shiga-like toxins [PDF]
Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
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