Results 11 to 20 of about 9,827 (181)

Molecular Biology of Escherichia coli Shiga Toxins’ Effects on Mammalian Cells [PDF]

open access: yesToxins, 2020
Shiga toxins (Stxs), syn. Vero(cyto)toxins, are potent bacterial exotoxins and the principal virulence factor of enterohemorrhagic Escherichia coli (EHEC), a subset of Shiga toxin-producing E. coli (STEC).
Christian Menge
doaj   +2 more sources

A High-Throughput, Precipitating Colorimetric Sandwich ELISA Microarray for Shiga Toxins [PDF]

open access: yesToxins, 2014
Shiga toxins 1 and 2 (Stx1 and Stx2) from Shiga toxin-producing E. coli (STEC) bacteria were simultaneously detected with a newly developed, high-throughput antibody microarray platform.
Andrew Gehring   +11 more
doaj   +2 more sources

P1PK blood group antigens in birds: implications for veterinary blood transfusion, human and pet health [PDF]

open access: yesBMC Veterinary Research
Background The P1PK blood group system in humans, composed of three glycosphingolipid antigens, plays a significant role in transfusion medicine. These antigens are synthesized by the enzyme α1,4-galactosyltransferase, encoded by the A4GALT gene, and ...
Anna Bereznicka   +9 more
doaj   +2 more sources

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

open access: yesToxins, 2010
Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee   +2 more
exaly   +3 more sources

The Interactions of Human Neutrophils with Shiga Toxins and Related Plant Toxins: Danger or Safety?

open access: yesToxins, 2012
Shiga toxins and ricin are well characterized similar toxins belonging to quite different biological kingdoms. Plant and bacteria have evolved the ability to produce these powerful toxins in parallel, while humans have evolved a defense system that ...
Maurizio Brigotti, Brigotti Maurizio
exaly   +3 more sources

Detection of Shiga Toxins by Lateral Flow Assay [PDF]

open access: yesToxins, 2015
Shiga toxin-producing Escherichia coli (STEC) produce shiga toxins (Stxs) that can cause human disease and death. The contamination of food products with STEC represents a food safety problem that necessitates rapid and effective detection strategies to ...
Kathryn H. Ching   +5 more
doaj   +2 more sources

Do the A Subunits Contribute to the Differences in the Toxicity of Shiga Toxin 1 and Shiga Toxin 2? [PDF]

open access: yesToxins, 2015
Shiga toxin producing Escherichia coli O157:H7 (STEC) is one of the leading causes of food-poisoning around the world. Some STEC strains produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2) or variants of either toxin, which are critical for the ...
Debaleena Basu, Nilgun E. Tumer
doaj   +3 more sources

Obtaining and Characterization of Hybridomas Producing Monoclonal Antibodies to Shiga-Like Toxins of I and II Types

open access: yesПроблемы особо опасных инфекций, 2021
Objective – obtaining and characterization of hybrid cell lines producing monoclonal antibodies against I and II types of shiga-like toxins.Materials and methods.
G. V. Kuklina   +6 more
doaj   +1 more source

Shiga and Shiga-like toxins [PDF]

open access: yesMicrobiological Reviews, 1987
Introduction . 206 Shiga Toxin in Shigella Spp. . 207 History . 207 Purification and Structure . 207 Mode of Action . 208 Receptor binding and internalization . 208 Inhibition of protein synthesis . 209 Immunology and Immunochemistry . 209 Genetics . 210 Role of Toxin in Disease . 210 Dysentery . 210 Diarrhea .210 HUS . 211 Shiga-like toxins in E. Coli
O'Brien, Alison D., Holmes, Randall K.
openaire   +2 more sources

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