Results 11 to 20 of about 9,721 (166)
AB5 Enterotoxin-Mediated Pathogenesis: Perspectives Gleaned from Shiga Toxins [PDF]
Toxins, 2022 Foodborne diseases affect an estimated 600 million people worldwide annually, with the majority of these illnesses caused by Norovirus, Vibrio, Listeria, Campylobacter, Salmonella, and Escherichia coli. To elicit infections in humans, bacterial pathogens
Erika N. Biernbaum, Indira T. Kudva
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Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy [PDF]
Toxins, 2020 Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB5 toxins.
Danyang Li +2 more
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Therapeutic Antibodies Against Shiga Toxins: Trends and Perspectives [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Shiga toxins (Stx) are AB5-type toxins, composed of five B subunits which bind to Gb3 host cell receptors and an active A subunit, whose action on the ribosome leads to protein synthesis suppression.
Izabella de Macedo Henrique +6 more
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Rapid Detection of Escherichia coli O157 and Shiga Toxins by Lateral Flow Immunoassays [PDF]
Toxins, 2016 Shiga toxin-producing Escherichia coli O157:H7 (STEC) cause food-borne illness that may be fatal. STEC strains enumerate two types of potent Shiga toxins (Stx1 and Stx2) that are responsible for causing diseases. It is important to detect the E.
Jinliang Wang +6 more
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Molecular Biology of Escherichia coli Shiga Toxins’ Effects on Mammalian Cells [PDF]
Toxins, 2020 Shiga toxins (Stxs), syn. Vero(cyto)toxins, are potent bacterial exotoxins and the principal virulence factor of enterohemorrhagic Escherichia coli (EHEC), a subset of Shiga toxin-producing E. coli (STEC).
Christian Menge
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Toxins, 2015 Shiga-like toxins (verotoxins) are responsible for the virulence associated with a variety of foodborne bacterial pathogens. Direct detection of toxins requires a specific and sensitive technique.
Christopher J Silva +2 more
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A High-Throughput, Precipitating Colorimetric Sandwich ELISA Microarray for Shiga Toxins [PDF]
Toxins, 2014 Shiga toxins 1 and 2 (Stx1 and Stx2) from Shiga toxin-producing E. coli (STEC) bacteria were simultaneously detected with a newly developed, high-throughput antibody microarray platform.
Andrew Gehring +11 more
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P1PK blood group antigens in birds: implications for veterinary blood transfusion, human and pet health [PDF]
BMC Veterinary ResearchBackground The P1PK blood group system in humans, composed of three glycosphingolipid antigens, plays a significant role in transfusion medicine. These antigens are synthesized by the enzyme α1,4-galactosyltransferase, encoded by the A4GALT gene, and ...
Anna Bereznicka +9 more
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Toxins, 2010 Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee +2 more
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The Interactions of Human Neutrophils with Shiga Toxins and Related Plant Toxins: Danger or Safety?
Toxins, 2012 Shiga toxins and ricin are well characterized similar toxins belonging to quite different biological kingdoms. Plant and bacteria have evolved the ability to produce these powerful toxins in parallel, while humans have evolved a defense system that ...
Maurizio Brigotti, Brigotti Maurizio
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