Results 81 to 90 of about 130,160 (165)
Acknowledgment to Reviewers of Toxins in 2020
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Toxins maintains its standards for the high quality of its published papers [...
Toxins Editorial Office Toxins Editorial Office
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OPPORTUNICTIC ENTEROBACTERIACAE AS THE CAUSE OF THE ACUTE DIARRHEA AND GUT DISBIOSIS
. Strains of Klebsiella pneumonia isolated from faces were studied to detect virulence factors of “classical” enteric pathogens causing acute diarrhea (Shigella, Salmonella, diarreagenic Escherichia coli). We haven’t detect in Klebsiella the genes encode
S. A. Egorova +2 more
doaj +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Influence of the Escherichia coli oxyR gene function on lambda prophage maintenance [PDF]
In Escherichia coli hosts, hydrogen peroxide is one of the factors that may cause induction of lambda prophage. Here, we demonstrate that H2O2-mediated lambda prophage induction is signiWcantly enhanced in the oxyR mutant host. The mRNA levels for cI
Łoś, Marcin +19 more
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KAT8‐Low Osteosarcoma Suppresses Cisplatin Sensitivity via H4K16ac‐Mediated Cell Apoptosis
The scientific significance of this study is highlighted below: (1) Data mining and clinical discovery: These findings establish a direct clinical link between the KAT8–H4K16ac axis and chemotherapy response in osteosarcoma. (2) Multi‐omics and machine‐learning integration: We integrated proteomics and CUT&Tag multi‐omics to elucidate how chromatin ...
Zhenqun Zhao +12 more
wiley +1 more source
Shiga toxins (Stxs) also called Verocytotoxins (Vtxs) and Shiga-like toxins (SLTs), are bacterial toxins produced by some members of the Enterobacteriaceaeparticulary Shigella dysenteriae and Escherichia coli 0157:H7 as well asAcinetobacter spp ...
Human, Izanne Susan +3 more
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Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source
UV-Sensitivity of Shiga Toxin-Converting Bacteriophage Virions Φ24B, 933W, P22, P27 and P32
Shiga toxin-converting bacteriophages (Stx phages) are present as prophages in Shiga toxin-producing Escherichia coli (STEC) strains. Theses phages can be transmitted to previously non-pathogenic E.
Sylwia Bloch +8 more
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ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD) lacks effective pharmacological therapies and is strongly associated with excessive fructose consumption. Ferroptosis and autophagy dysregulation are increasingly recognized as key drivers of MAFLD progression.
Puyu Zhang +11 more
wiley +1 more source
We developed hierarchical chiral Au nanostructures on Au coral structures on transparent conductive oxide substrates using only electrochemical methods. By controlling the interaction between [AuCl4]– and cysteine, we successfully tuned the morphology and circular dichroism of the resulting Au nanostructures.
Kenta Nakagawa +7 more
wiley +1 more source

