Results 101 to 110 of about 9,827 (181)

Efficacy of Nivolumab in Chemotherapy‐Resistant Mesothelioma of the Tunica Vaginalis Testis: A Case Report

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Mesothelioma of the tunica vaginalis testis is a rare neoplasm, accounting for less than 1% of all mesothelioma cases. Due to the rarity of this disease, a standard treatment has not been established. Clinical management is generally adapted from the strategies used for pleural mesothelioma.
Haruki Koyanagi, Takashi Kawahara, Natsuki Inagawa, Miho Shiga, Hiromichi Sakurai, Akane Yamaguchi, Kouzaburou Tanuma, Satoshi Nitta, Kosuke Kojo, Masanobu Shiga, Yoshiyuki Nagumo, Atsushi Ikeda, Shuya Kandori, Akio Hoshi, Hiromitsu Negoro, Hitomi Kawai, Daisuke Matsubara, Hiroyuki Nishiyama   +17 more
wiley   +1 more source

Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins. [PDF]

Toxins (Basel), 2021
Selyunin AS, Nieves-Merced K, Li D, McHardy SF, Mukhopadhyay S.   +4 more
europepmc   +1 more source

Effect of Porphyromonas gingivalis Infection on PGC‐1α in Skeletal Muscle After Endurance Training In Vivo

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives It is well known that Porphyromonas gingivalis, a major pathogen in periodontitis, causes systemic diseases. This study investigated the expression of PGC‐1α (the most important factor in muscle mitochondria synthesis) following endurance training to clarify the relationship between P.
Kairi Hayashi, Yasuo Takeuchi, Hiroaki Kobayashi, Gen Tanabe, Hiroshi Churei, Toshiaki Ueno, Kenji Fueki   +6 more
wiley   +1 more source

A Prospective Observational Study of Anamorelin During Chemoimmunotherapy in Non‐Small Cell Lung Cancer With Cachexia (SPIRAL‐ANA)

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The prognosis of patients with advanced non‐small cell lung cancer (NSCLC) complicated by cancer cachexia remains poor. Anamorelin, a ghrelin receptor agonist, has been approved only in Japan for the treatment of cancer cachexia.
Kenji Morimoto, Junji Uchino, Makoto Hibino, Yuki Takeyasu, Ken Yamamoto, Yoshie Morimoto, Yusuke Chihara, Takayuki Nakano, Hiroyasu Kaneda, Shunya Tanaka, Shinsuke Ogusu, Yasuhiro Goto, Takashi Nomizo, Takayo Ota, Hiroaki Tsukamoto, Yoshizumi Takemura, Katsumi Nakatomi, Hayato Koba, Kohei Yoshimine, Takayuki Shimose, Tadaaki Yamada, Koichi Takayama   +21 more
wiley   +1 more source

Optimization of Dual‐Bacteriophage Magnetic Nanoprobe for the Detection of Staphylococcus aureus and Pseudomonas aeruginosa

Macromolecular Bioscience, Volume 26, Issue 8, August 2026.
The optimal densities of two bacteriophages on magnetic nanoparticles are determined in order to make magnetic nanoprobes. These nanoprobes can bind bacteria in 10 min and be quickly retrieved from aqueous samples for later analysis. The nanoprobes are capable of capturing Staphylococcus aureus and Pseudomonas aeruginosa with concentrations as low as ...
Jun‐Ping Zhang, Hsin‐Yi Lin
wiley   +1 more source

Efficacy of Adjuvant Interferon‐β Versus Observation for Resected Nail Apparatus Melanoma: A Multicenter Retrospective Study

The Journal of Dermatology, Volume 53, Issue 8, Page 1124-1132, August 2026.
ABSTRACT Nail apparatus melanoma (NAM) is a biologically and clinically distinct subtype of melanoma; however, the efficacy of adjuvant interferon (IFN) therapy in this population remains unclear. We conducted a multicenter retrospective study to compare adjuvant IFN‐β (adj‐IFN) with observation (OBS) in patients with resected stage IIB, IIC, or III ...
Takaya Komori, Eiji Nakano, Yukiko Kiniwa, Shoichiro Mori, Sotaro Yamamoto, Hiroshi Kato, Shusuke Yoshikawa, Koji Yoshino, Megumi Aoki, Tatsuya Takenouchi, Takuya Maeda, Keijun Yoshino, Shuichi Ohe, Kenta Nakama, Hideyuki Ishikawa, Yoshiyuki Nakamura, Toshihiro Takai, Takamichi Ito, Hiroshi Kitagawa, Hiraku Kokubu, Naohito Hatta, Takeru Funakoshi, Toshihiko Hoashi, Takayuki Suyama, Susumu Fujiwara, Mamiko Masuzawa, Hiroshi Uchi, Takuya Miyagawa, Soichiro Kado, Yuki Yamamoto, Jun Asai, Junji Kato, Taku Maeda, Natsuki Baba, Yukihiko Kato, Kohei Oashi, Takeo Maekawa, Shunichi Jinnai, Aya Nishizawa, Ko Kagoyama, Atsushi Otsuka, Katsuhiko Nishihara, Dai Ogata, Kenjiro Namikawa, Yasuhiro Nakamura, Shigeto Matsushita   +45 more
wiley   +1 more source

Using Ongoing Wildlife Surveillance Programs to Monitor Antibiotic Resistant Bacteria in the Environment

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Screening of ESBL‐, pAmpC‐ and carbapenemase‐producing Escherichia coli among Swedish wildlife demonstrated a low occurrence of antibiotic resistance in wild animals. Only two ESBL/pAmpC‐producers were detected in red foxes originating from highly populated areas.
María Rincón‐Gracia, Stefan Börjesson, Robert Söderlund, Hanna Woksepp, Aleksija Neimanis, Henrik Uhlhorn, Thomas Rosendal, David Winlund, Hugo Uddströmer, Josef D. Järhult, Jonas Bonnedahl   +10 more
wiley   +1 more source

Alcohol‐Induced Early‐Stage Liver Injury Contributes to Increases in Voluntary Alcohol Intake and Cognitive Deficits in Mice

Alcohol, Clinical and Experimental Research, Volume 50, Issue 8, August 2026.
While the liver–brain axis is well‐characterized in alcohol‐related disorders, the impact of alcohol‐associated liver disease (ALD) on alcohol use disorder (AUD)‐related behaviors remains unclear. This study investigated the effects of early‐stage ALD on alcohol consummatory behavior and cognitive function in C57BL/6 mice. Early ALD induced a transient
Samantha G. Skinner, Eliana G. Aleman, Julio Rivera, Nikhila Kalapatapu, Dhruv Kantilal, Daryl L. Davies, Liana Asatryan   +6 more
wiley   +1 more source

The Role of Escherichia coli Shiga Toxins in STEC Colonization of Cattle. [PDF]

Toxins (Basel), 2020
Menge C.
europepmc   +1 more source

Flecainide binding dynamics in voltage‐gated sodium channels: A comparative isoform analysis of the state‐dependent block

British Journal of Pharmacology, Volume 183, Issue 15, Page 4145-4162, August 2026.
Background and Purpose Local anaesthetics and class I anti‐arrhythmic drugs block voltage‐gated Na+ channels, but the molecular basis for the isoform differences in drug sensitivity remains unclear. Understanding these mechanisms is essential for optimizing therapeutic efficacy and safety.
Tatsuo Munakata, Etsuko Kumada, Nao Katayama, Hiroki Nakagawa, Akihiko Sunami   +4 more
wiley   +1 more source