Results 91 to 100 of about 130,160 (165)
Small, EarlyView.Cstalk, a giant fibrous protein, selectively partitions into the dextran‐rich phase in polyethylene glycol/dextran aqueous two‐phase systems, functioning as a recruiter for proteins of interest. This phase‐selective recruitment can be extended to fungal cell walls, enabling the targeted localization of enzymes and enhancing antifungal activity through ...
Ayasa Nagatani +6 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster +13 more
wiley +2 more sources
VIEW, EarlyView.Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley +1 more source
Shiga toxins and stx phages: highly diverse entities [PDF]
, 2015 Shiga toxins are the main virulence factors of a group of Escherichia coli strains [Shiga toxin-producing E. coli (STEC)] that cause severe human diseases, such as haemorrhagic colitis and haemolytic–uraemic syndrome.
Lucchesi, Paula Maria Alejandra +1 more
core +1 more source
Molecular confirmation of some virulence genes of E. coli isolated from lambs' colibacillosis [PDF]
Iraqi Journal of Veterinary SciencesColibacillosis is an infectious disease caused by pathogenic strains of E. coli, which are considered the most common and significant bacteria that cause dysentery or diarrhea in lambs.
Khalid Muhammad, Mohammad A. Hamad
doaj +1 more source
Cancer Science, EarlyView.This study demonstrates the selective depletion of tumor‐associated macrophages (TAMs) by targeting CSF1R through near‐infrared photoimmunotherapy (NIR‐PIT). Using a combination of anti‐CSF1R Fab‐IR700 conjugates and localized light irradiation, we achieved tumor suppression and durable antitumor immunity without systemic toxicity.
Kohei Nakajima +6 more
wiley +1 more source
Previous PCR data for Shiga toxins by conventional and molecular methods and WGS data.
, 2021 Previous PCR data for Shiga toxins by conventional and molecular methods and WGS data.
Robin King (4026194) +7 more
core +1 more source
Recent Advancements in Technologies to Detect Enterohaemorrhagic Escherichia coli Shiga Toxins. [PDF]
J Microbiol Biotechnol, 2023 Kim J, Lee JB, Park J, Koo C, Lee MS.
europepmc +1 more source
Inborn errors of immunity in children with neuroinflammation
Developmental Medicine &Child Neurology, EarlyView.Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2018 Strains of Shiga toxin-producing Escherichia coli (STEC) can cause the severe Hemolytic Uremic Syndrome (HUS). Shiga toxins are protein toxins that bind and kill microvascular cells, damaging vital organs.
Matias Fingermann +9 more
doaj +1 more source