Results 121 to 130 of about 20,091 (215)
A practical one‐pot strategy for the synthesis of ortho‐amide‐functionalized TMP‐iodonium(III) salts has been developed. These iodonium salts exhibited distinct reactivities toward N‐, O‐, and S‐nucleophiles, facilitating arylocyclization and producing a variety of benzo‐fused heterocycles under mild conditions.
Naoki Miyamoto +4 more
wiley +1 more source
Recent Advancements in Technologies to Detect Enterohaemorrhagic Escherichia coli Shiga Toxins. [PDF]
Kim J, Lee JB, Park J, Koo C, Lee MS.
europepmc +1 more source
Shiga Toxin 1a Blunts Shiga Toxin 2a-pathogenic Effects in Blood
ABSTRACT Once released into human blood, Shiga toxins (Stx) interact with platelets and leukocytes, stimulating them to form aggregates and to release pathogenic extracellular vesicles (EV) containing Stx. These EV are considered the trigger driving the transition from bloody diarrhea to the life-threatening hemolytic uremic syndrome (
Elisa, Varrone +11 more
openaire +2 more sources
STUDIES ON THE TOXIN PRODUCTION OF THE SHIGA BACILLI [PDF]
1. The S, R, and Rn variants of the Shiga bacillus are equally toxic. 2. The effect of the toxin upon rabbits is the same, whether it is derived from filtrates of broth cultures (3 to 6 days old), or is obtained by autolysis of the killed bacteria, grown on agar surface.
openaire +2 more sources
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source
Toxins in Fermented Foods: Prevalence and Preventions—A Mini Review
Fermented foods (FF) are widely consumed around the world, and FF are one of the prime sources of toxins and pathogenic microbes that are associated with several foodborne outbreaks.
Bhagavathi Sundaram Sivamaruthi +2 more
doaj +1 more source
Shiga toxin 2 translocation across intestinal epithelium is linked to virulence of Shiga toxin-producing Escherichia coli in humans [PDF]
Shiga toxin-producing Escherichia coli (STEC) are characterized by the release of potent Shiga toxins (Stx), which are associated with severe intestinal and renal disease.
Beltrametti +7 more
core +2 more sources
Cell Mechanics in Cancer: Integrating Mechanotransduction Pathways Within the Tumor Microenvironment
ABSTRACT Single‐cell mechanical properties such as stiffness, elasticity, and viscosity, are crucial in governing biological processes like migration, proliferation, and differentiation. In cancer, the mechanical properties of cells undergo significant alterations, which contribute to tumor growth, metastasis, and resistance to therapy.
Merve Sevgi +7 more
wiley +1 more source
Flagellin induces β-defensin 2 in human colonic ex vivo infection with enterohemorrhagic Escherichia coli [PDF]
Enterohemorrhagic E. coli (EHEC) is an important foodborne pathogen in the developed world and can cause life-threatening disease particularly in children.
Chan, Simon +6 more
core +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) is a heterogeneous malignancy characterized by high mortality rates. This article presents a discussion of the role of ZNF652 in HCC cell proliferation and apoptosis, thereby identifying a new target for HCC treatment. The expression levels of ZNF652, circRHOT1, and SLC38A6 in HCC and healthy cells were analyzed.
Kang Chen +7 more
wiley +1 more source

