PGLYRP4 Enhances Shigella flexneri Virulence by Promoting virF Transcription via the CpxA/R Two-Component System. [PDF]
MicrobiologyopenShigella can use the host's innate immune system to optimize the expression of its virulence factors. The PGLYRP4 protein, a member of the host's innate immune system, increases VirF expression in Shigella by stimulating the CpxA/R TCS, thereby enhancing the expression of the virulence system.
Trirocco R, Prosseda G.
europepmc +2 more sources
Antimicrobial Resistance in Human and Animal Pathogens in Zambia, Democratic Republic of Congo, Mozambique and Tanzania: An Urgent Need of a Sustainable Surveillance System. [PDF]
, 2013 A review of the published and unpublished literature on bacterial resistance in human and animals was performed. Sixty-eight articles/reports from the Democratic Republic of Congo (DRC), Mozambique, Tanzania and Zambia were reviewed.
Matee, Mecky +2 more
core +1 more source
Shigella sonnei: virulence and antibiotic resistance
Archives of Microbiology, 2020 Shigella sonnei is the emerging pathogen globally, as it is the second common infectious species of shigellosis (bloody diarrhoea) in low- and middle-income countries (LMICs) and the leading one in developed world.
A. A. Shad, Wajahat Ahmed Shad
semanticscholar +1 more source
PLoS Neglected Tropical Diseases, 2020 Culture-independent diagnostics have revealed a larger burden of Shigella among children in low-resource settings than previously recognized. We further characterized the epidemiology of Shigella in the first two years of life in a multisite birth cohort.
E. R. Rogawski McQuade +28 more
semanticscholar +1 more source
Functional antibodies as immunological endpoints to evaluate protective immunity against Shigella
Human Vaccines & Immunotherapeutics, 2020 The development, clinical advancement and licensure of vaccines, and monitoring of vaccine effectiveness could be expedited and simplified by the ability to measure immunological endpoints that can predict a favorable clinical outcome.
Esther Ndungo, Marcela F. Pasetti
doaj +1 more source
Ho Chi Minh City Open University Journal of Science - Engineering and Technology, 2020 Indigenous microorganism (IMO) has great potential for agricultural uses since they have high ability in biodegradation, nitrogen fixation, phosphate solubilization, plant growth hormone production as well as bio-control.
Le Thi Xa, Nguyen Khoi Nghia
doaj +1 more source
Molecular mechanisms of cell–cell spread of intracellular bacterial pathogens [PDF]
Open Biology, 2013 Several bacterial pathogens, including Listeria monocytogenes, Shigella flexneri and Rickettsia spp., have evolved mechanisms to actively spread within human tissues.
Keith Ireton
doaj +1 more source
Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]
, 2016 Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies +10 more
core +4 more sources
Identification of critical residues of the serotype modifying O-acetyltransferase of Shigella flexneri [PDF]
, 2016 BACKGROUND Thirteen serotypes of Shigella flexneri (S. flexneri) have been recognised, all of which are capable of causing bacillary dysentery or shigellosis. With the emergence of the newer S.
Thanweer, Farzaana, Verma, Naresh K
core +1 more source
Detection of 5 kinds of common foodborne pathogens by GeXP multiplex polymerase chain reaction
Zhongguo shipin weisheng zazhi, 2020 Objective To establish a new and rapid GeXP (GenomeLabTM eXpress Profiling) based multiplex polymerase chain reaction (PCR) assay for the detection of five common foodborne pathogens. Methods Nucleotide sequences of specific gene (invA, rfbE, PfrA, IpaH,
Mengjie YANG +3 more
doaj +1 more source