Results 51 to 60 of about 142,788 (241)
BMEMat, EarlyView.The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng +10 more
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2018 The article summarises materials on the certification of the industry reference standard of Schigella sonnei polysaccharide dysentery vaccine (commercial name — Schigellvac).
V. A. Volkov +5 more
doaj +1 more source
Vaccines against gastroenteritis, current progress and challenges
Gut Microbes, 2020 Enteric viral and bacterial infections continue to be a leading cause of mortality and morbidity in young children in low-income and middle-income countries, the elderly, and immunocompromised individuals.
Hyesuk Seo, Qiangde Duan, Weiping Zhang
doaj +1 more source
Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis. [PDF]
Clin Transl SciABSTRACT Increasing antimicrobial resistance poses a serious challenge for the treatment of Shigella infections, and there is an urgent need for alternative antibacterial treatments. We conducted a clinical trial to investigate the efficacy of oral tebipenem pivoxil, compared to intravenous ceftriaxone, in Bangladeshi children with shigellosis.
Zhang CX +12 more
europepmc +2 more sources
Medium alkalization due to carbon metabolism is largely responsible for inhibition of bacterial growth by Vibrio cholerae supernatants [PDF]
, 2017 Vibrio cholerae is the causative agent of the diarrheal disease cholera. Many Vibrio species secrete antimicrobial factors, though the identity of such a factor has not been determined for any V. cholerae strain.
Becker, Miranda
core +1 more source
Cytoskeleton, EarlyView.ABSTRACT Septins are conserved GTP‐binding proteins that play key roles in cell division, mitochondrial dynamics and immune responses. Despite their importance to human health, pharmacological compounds to modify septins remain limited. Forchlorfenuron (FCF) was the first small molecule identified to modify septins, disrupting their organisation and ...
Dominik Brokatzky +4 more
wiley +1 more source
Interplay between septins and ubiquitin-mediated xenophagy during Shigella entrapment
Autophagy Reports, 2023 Septins are cytoskeletal proteins implicated in numerous cellular processes including cytokinesis and morphogenesis. In the case of infection by Shigella flexneri, septins assemble into cage-like structures that entrap cytosolic bacteria targeted by ...
Damián Lobato-Márquez +5 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza +4 more
wiley +1 more source
EFFECT OF SOME ANTIBIOTIC ON SOME SPECIES OF SALMONELLA AND SHIGELLA ISOLATED FROM DIARRHEA CASES. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 This study included (50) Stool specimens which were collected from various age groups from (4 months to 50 years) of patients suffering from acute diarrhea (bloody and watery), from hospitals in Baghdad, These specimens were collected and cultured on ...
AFAF A. YOUSIF, ASAAD K.TALAL
doaj +1 more source
Progressive Mauve: Multiple alignment of genomes with gene flux and rearrangement [PDF]
, 2009 Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms.
Darling, Aaron E. +2 more
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