Results 61 to 70 of about 54,989 (228)

Identification of Shiga-Toxin-Producing Shigella Infections in Travel and Non-Travel Related Cases in Alberta, Canada

Toxins, 2021
It has long been accepted that Shiga toxin (Stx) only exists in Shigella dysenteriae serotype 1. However, in recent decades, the presence of Shiga toxin genes (stx) in other Shigella spp. have been reported. We screened 366 Shigella flexneri strains from
Shuai Zhi, Brendon D. Parsons, Jonas Szelewicki, Yue T. K. Yuen, Patrick Fach, Sabine Delannoy, Vincent Li, Christina Ferrato, Stephen B. Freedman, Bonita E. Lee, Xiao-Li Pang, Linda Chui   +11 more
doaj   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, Volume 293, Issue 5, Page 1285-1296, March 2026.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Genomic insights into Shigella species isolated from small ruminants and manure in the North West Province, South Africa

Applied Microbiology and Biotechnology
This study investigated Shigella species’ antibiotic resistance patterns and genomic characteristics from small ruminants and manure collected in Potchefstroom, North West, South Africa. Whole genome sequencing was used to determine resistome profiles of
Tshepang Motlhaping, Tsepo Ramatla, Oriel Thekisoe, Ntelekwane George Khasapane, Kgaugelo E. Lekota   +4 more
doaj   +1 more source

Shigella flexneri Regulation of ARF6 Activation during Bacterial Entry via an IpgD-Mediated Positive Feedback Loop

mBio, 2015
Entry into cells is critical for virulence of the human bacterial pathogens Shigella spp. Shigella spp. induce membrane ruffle formation and macropinocytic uptake, but the events instigating this process are incompletely understood. The host small GTPase
Anna Cristina Garza-Mayers, Kelly A. Miller, Brian C. Russo, Dipal V. Nagda, Marcia B. Goldberg   +4 more
doaj   +1 more source

Prevalence of Plasmid-Mediated Determinants With Decreased Susceptibility to Azithromycin Among Shigella Isolates in Anhui, China

Frontiers in Microbiology, 2020
ObjectiveThe aims of this study were to describe azithromycin (AZM) susceptibility patterns among Shigella isolates in Anhui, China and identify predictors of resistance with mobile element-mediated genes.MethodsA total of 517 non-duplicate Shigella ...
Yanyan Liu, Yanyan Liu, Yanyan Liu, Hongru Li, Na Lv, Yalong Zhang, Xihai Xu, Ying Ye, Ying Ye, Ying Ye, Yufeng Gao, Yufeng Gao, Yufeng Gao, Jiabin Li, Jiabin Li, Jiabin Li, Jiabin Li   +16 more
doaj   +1 more source

The Autotransporter IcsA Promotes Shigella flexneri Biofilm Formation in the Presence of Bile Salts

Infection and Immunity, 2019
Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism.
Volkan K Köseoğlu, Chelsea Hall, E. Rodriguez-Lopez, H. Agaisse   +3 more
semanticscholar   +1 more source

Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development

Tropical Medicine &International Health, Volume 31, Issue 3, Page 295-306, March 2026.
ABSTRACT Objectives The primary objectives of this study are to (1) summarise the current landscape of ETEC vaccine development by describing, characterising and comparing ETEC vaccine candidates in clinical development, (2) assess key characteristics of the phases 1, 2 and 3 clinical trials that have been designed to evaluate ETEC vaccines in ...
Vaidehi Nafade, Naheemot O. Sule, Yang Zhang, Angelina Sassi, Nicole E. Basta   +4 more
wiley   +1 more source

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility

mBio, 2017
Dynamin-like guanylate binding proteins (GBPs) are gamma interferon (IFN-γ)-inducible host defense proteins that can associate with cytosol-invading bacterial pathogens.
Anthony S. Piro, Dulcemaria Hernandez, Sarah Luoma, E. Feeley, Ryan H. Finethy, Azeb Yirga, Eva‐Maria Frickel, C. Lesser, J. Coers   +8 more
semanticscholar   +1 more source

Computational Analysis of a GST‐Based Long‐Wave Infrared Microring Resonator on a ZnSe Platform as a Photonic Sensor

Advanced Photonics Research, Volume 7, Issue 2, February 2026.
A Ge2Sb2Te5 (GST)‐based microring resonator is designed and simulated on a ZnSe‐platform that operates in the long‐wave infrared (LWIR) wavelength of 8 μm. The structure demonstrates strong power confinement and high Q‐factor. GST resonator is used for gas and biosensing applications.
Tanzina Rahman, Md. Islahur Rahman Ebon, Amrita Kumar Sana, Jaker Hossain   +3 more
wiley   +1 more source

GNPS Untargeted GC‐MS Metabolomic Analysis of Essential Oils From Duguetia lanceolata and Evaluation of Antimicrobial Activity

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Untargeted metabolomic analysis of the essential oil of D. lanceolata leaves collected in winter revealed that they are mostly composed of sesquiterpenes, while those collected in autumn showed a predominance of monoterpenes. Both essential oils displayed antimicrobial activity against bacterial and fungal species.
Jackson Monteiro, Geovanna N. Antonelli, Erick P. Dantas, Simone S. Grecco, Marisi G. Soares, João Henrique G. Lago, Renata C. Pascon, Marcelo A. Vallim, Patricia Sartorelli   +8 more
wiley   +1 more source