The Rising Dominance of Shigella sonnei: An Intercontinental Shift in the Etiology of Bacillary Dysentery. [PDF]
, 2015 Shigellosis is the major global cause of dysentery. Shigella sonnei, which has historically been more commonly isolated in developed countries, is undergoing an unprecedented expansion across industrializing regions in Asia, Latin America, and the Middle
Baker, Stephen +2 more
core +6 more sources
Deletion of toxin–antitoxin systems in the evolution of Shigella sonnei as a host-adapted pathogen [PDF]
, 2016 Pathogenic Shigella spp. are the leading cause of bacterial dysentery, with Shigella flexneri and Shigella sonnei accounting for around 90% of cases worldwide. While S.
McVicker, G, Tang, CM
core +1 more source
Impact of insertion sequences on convergent evolution of Shigella species.
PLoS Genetics, 2020 Shigella species are specialised lineages of Escherichia coli that have converged to become human-adapted and cause dysentery by invading human gut epithelial cells.
Jane Hawkey +4 more
doaj +1 more source
Evaluation of a Live Attenuated S. sonnei Vaccine Strain in the Human Enteroid Model
Pathogens, 2021 Shigella is a leading cause of bacillary dysentery worldwide, responsible for high death rates especially among children under five in low–middle income countries.
Giulia Pilla +6 more
doaj +1 more source
Clinical implications of reduced susceptibility to fluoroquinolones in paediatric Shigella sonnei and Shigella flexneri infections. [PDF]
, 2015 OBJECTIVES: We aimed to quantify the impact of fluoroquinolone resistance on the clinical outcome of paediatric shigellosis patients treated with fluoroquinolones in southern Vietnam.
Baker, Stephen +17 more
core +1 more source
A Cryptic Plasmid from Shigella sonnei [PDF]
Microbiology, 1983 pNZ500 is a 1.5 kb cryptic plasmid from a Shigella sonnei isolate. It was introduced into Escherichia coli by cotransformation, where it is maintained at about 30 copies per chromosome equivalent. Hybridization studies show that pNZ500 exhibits a high level of sequence similarity to other 1.5 kb plasmids found in different S. sonnei isolates but shares
J E, Croft, P L, Bergquist, D, Lane
openaire +2 more sources
Establishment of a Controlled Human Infection Model with a Lyophilized Strain of
mSphere, 2020 Controlled human infection models (CHIMs) are useful for vaccine development. To improve on existing models, we developed a CHIM using a lyophilized preparation of Shigella sonnei strain 53G produced using current good manufacturing practice (cGMP ...
Robert W. Frenck +14 more
doaj +1 more source
Symptomatic Shigella sonnei urinary tract infection [PDF]
Journal of Clinical Microbiology, 1995 The clinical course for a patient with symptomatic urinary tract infection due to Shigella sonnei is described. The role of Shigella spp. as urinary pathogens is reviewed.
C J, Papasian +2 more
openaire +2 more sources
Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core +2 more sources
The multivalent adhesion molecule SSO1327 plays a key role in Shigella sonnei pathogenesis : SSO1327 is an adhesin required for S. sonnei pathogenesis [PDF]
, 2015 Shigella sonnei is a bacterial pathogen and causative agent of bacillary dysentery. It deploys a type III secretion system to inject effector proteins into host epithelial cells and macrophages, an essential step for tissue invasion and immune evasion ...
Eldomany, R A +8 more
core +2 more sources