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The Shikimate Pathway: Biosynthesis of Phenolic Products from Shikimic Acid
2016Like other amino acids, the aromatic amino acids phenylalanine, tyrosine, and tryptophan are vitally important for protein synthesis in all organisms. However, while animals can synthesize tyrosine via oxidation of phenylalanine, they can synthesize neither phenylalanine itself nor tryptophan and so these essential amino acids must be obtained in the ...
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The shikimate pathway: I. - Preparation of 3-3H, 4-3H and 2,4-3H2 D-shikimic acid
Biochimie, 1973Summary The preparation of three different isotopic species of D-shikimate is described. 3- 3 H D-shikimate was obtained by ( 3 H) borohydride reduction of methyl 3-dehydroshikimate and separation of the resulting 3- 3 H epimers. 4- 3 H-D-shikimate was prepared through reduction of 4-dehydroquinic acid to 4- 3 H quinic acid by ( 3 H) borohybride ...
P, Dansette, R, Azerad
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Uptake of shikimate pathway intermediates by intact chloroplasts
Phytochemistry, 1991Abstract In intact chloroplasts isolated from barley, the rate of aromatic amino acid synthesis from 3-dehydroquinate (DHQ), 3-dehydroshikimate (DHS) or shikimate (SKA), 2 mM each, and [1- 14 C]phosphoenolpyruvate (PEP) was 2.5-, 6- and 2.5-fold compared with the rate from photosynthetically fixed CO 2 and [1- 14 C]PEP.
Carola Leuschner, Gernot Schultz
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The shikimate pathway and aromatic amino Acid biosynthesis in plants.
Annual Review of Plant Biology, 2012Hiroshi A. Maeda, N. Dudareva
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Aspects of the Enzymology of the Shikimate Pathway
1996These are the concluding words of an appreciation of the life and scientific work of Johan Frederik Eykman (1851–1915) published in Recueil Travaux Chimique des Pays-Bas, XXXV, 365–420 (1916), written by A. F.Holleman. It is very doubtful if the writer appreciated, at the time, the full significance of his words.
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Multifunctional Enzymes in the shikimate pathway
2018Multifunctional enzymes are instances of natural fusion proteins, possessing multiple catalytic activities. Via the close proximity of their catalytic domains, they take advantage from concentration of the reactants and may feature allosteric regulation and substrate channeling effects.
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Journal of Industrial Microbiology & Biotechnology, 2019
Yinbiao Xu +5 more
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Yinbiao Xu +5 more
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Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
Nature Reviews Drug Discovery, 2020Anwesha Dey +2 more
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