Results 61 to 70 of about 2,494,268 (274)

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

open access: yesAdvanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen   +14 more
wiley   +1 more source

PERANCANGAN KAPAL UNTUK MENUNJANG KEGIATAN PARIWISATA DI WADUK JATILUHUR, PURWAKARTA

open access: yesKapal, 2012
Jatiluhur had the very big tourism potency so that it was required the supporting mean such as the tour ship which was better than the wooden ship. The research about the tour ship design having a catamaran hull form was expected to help the development ...
Parlindungan Manik, Ahmad Didi Ahmadi
doaj   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

open access: yesAdvanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka   +3 more
wiley   +1 more source

Ship Antiballistic Missile Response

open access: yes, 2006
Part of the TSSE Team 2006 - SABR: Ship Anti Ballistic Response projectApproved for public release, distribution ...
Papoulias, Fotis   +15 more
core   +2 more sources

The Surface Warfare Test Ship [PDF]

open access: yes, 2000
Part of TSSE Team 1999 - The Surface Warfare Test Ship projectThe views expressed in this report are those of the authors and do not necessarily relfect the offical policy or position of the Department of Defense or the U.S.
Harney, Robert C.   +6 more
core   +2 more sources

Mean-Square Non-Local Stability of Ship in Storm Conditions of Operation

open access: yesPolish Maritime Research, 2019
The purpose of the paper is to create a method for studying nonlocal stability in the mean and in the mean square of the ship, positioned on the beam of an intensive wind–waves mode, which is based on the use of the correlation theory of random functions
Nekrasov Valeriy
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Application of analytical target cascading method in multidisciplinary design optimization of ship conceptual design

open access: yesZhongguo Jianchuan Yanjiu, 2017
[Objectives] Ship conceptual design requires the coordination of many different disciplines for comprehensive optimization, which presents a complicated system design problem affecting several fields of technology.
WANG Jian   +3 more
doaj   +1 more source

High‐Power Hybrid Nanogenerator With Multi‐Degree‐of‐Freedom Mechanical Coupling for Harvesting Water Wave Energy

open access: yesAdvanced Science, EarlyView.
A high‐power hybrid nanogenerator (HP‐HNG) with multi‐degree‐of‐freedom mechanical coupling is reported, integrating multi‐directional wave energy for output to achieve 1 + 1 > 2 energy harvesting. The HP‐HNG achieves a peak output power of 0.764 W, corresponding to a peak power density of 127.303 W m−3. At a wave frequency of 1 Hz, the HP‐HNG delivers
Shuai Ding   +9 more
wiley   +1 more source

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