The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Comorbidities, Routine Biomarkers and Early Septic Shock Occurrence in Patients with Sepsis: A Retrospective Longitudinal Study. [PDF]
Petrović J.
europepmc +1 more source
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
Central venous-arterial CO2 gap to arterial-central venous O2 content difference ratio in guiding of fluid resuscitation of patients with septic shock. [PDF]
Fang XW, Weng YR, Jiang X, Wu ZT, Ye GJ.
europepmc +1 more source
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu +11 more
wiley +1 more source
Septic cardiomyopathy: a rare and life-threatening complication of small intestinal perforation: A case report. [PDF]
Wang F, Ma R, Luo Y, Ma D, Xiao J.
europepmc +1 more source
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu +8 more
wiley +1 more source
Impact of Early versus Delayed Vasopressin Initiation on 28-Day Mortality in Older Adults with Septic Shock. [PDF]
Liu L, Shi H, Zhang L, Ma J.
europepmc +1 more source
Essential embryology for the Canadian pathologists’ assistant
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci +4 more
wiley +1 more source
Assessment of Early Antibiotic Administration for Patients With Sepsis in the Emergency Department: A Retrospective Observational Study at a Tertiary Care Hospital. [PDF]
Thomas A +9 more
europepmc +1 more source

