Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Serum HMGB1 as a biomarker and predictive model for pediatric septic shock: a cohort study. [PDF]
Wang B +5 more
europepmc +1 more source
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray +2 more
wiley +1 more source
Application of Infrared Thermography in Early Screening of Sepsis and Prediction of Septic Shock Risk: A Systematic Review. [PDF]
Du WY, Huang JT, Zhang ZP.
europepmc +1 more source
Impact of prehospital antibiotic therapy differs depending on septic shock origin. [PDF]
Jouffroy R +10 more
europepmc +1 more source
From proteomics to colloidal gold tests for urinary thrombomodulin: a prospective cohort study on accurate sepsis screening. [PDF]
Chen Q +9 more
europepmc +1 more source
Efficacy of thiamine (vitamin B1) in sepsis and septic shock: A meta-analysis of randomized controlled trials. [PDF]
Xu X +7 more
europepmc +1 more source
Pediatric Shock Across Acute Emergencies: Age Patterns, Etiologic Subtypes, and Bedside Clinical Indicators in a Single-Centre Cohort. [PDF]
Singer CE +11 more
europepmc +1 more source
Neglected Myiasis Wound Presenting With Septic Shock: A Case Report. [PDF]
Adhikari N, Das SK.
europepmc +1 more source

