Results 41 to 50 of about 610,317 (302)

Septic Shock

Veterinary Clinics of North America: Small Animal Practice, 1989
Septic shock is a life-threatening condition that results from the combined effects of bacteria and the host's chemical mediators of inflammation. Of particular detriment is the hyperdynamic and hypodynamic vasomotor instability that severely compromises the patient prior to the onset of overt bacteremia.
Resident, From the Department of Small Animal Clinical Sciences, University of Florida College of Veterinary Medicine, Gainesville, Florida ( host institution ), Goodwin, John-Karl ( author ), Schaer, Michael ( author )   +2 more
openaire   +3 more sources

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]

, 2007
Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias, Christoph Sucker, Zacharowski, Kai, Hartmann, Matthias, Kai Zacharowski, Matthias Thielmann, Sucker, Christoph, Sucker Christoph, Thielmann Matthias, Matthias Hartmann, Zacharowski Kai, Hartmann Matthias   +11 more
core   +1 more source

Managing septic shock [PDF]

F1000 Medicine Reports, 2010
Although several successful clinical trials in the last 2-3 years have been greeted with enthusiasm by intensivists, severe sepsis and septic shock still have increasing incidence and more or less unchanged mortality. Within the last few years, the progress in sepsis research covering definitions, epidemiology, pathophysiology, diagnosis, and standard ...
Gerlach, Herwig, Toussaint, Susanne
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Serum Soluble Endoglin in Pediatric Septic Shock Associated Multiple Organ Dysfunction Syndrome

, 2023
Background: Endothelial activation is a key driver of multiple organ dysfunction syndrome (MODS). Soluble endoglin (sENG) is expressed by mature and progenitor endothelial cells and thought to have angiogenic properties.
Weiss, Scott L., Haileselassie, Bereketeab, Zingarelli, Basilia, Lutfi, Riad, Bigham, Michael T., Thomas, Neal J., Schwarz, Adam J., Jain, Parag N., Fitzgerald, Julie C., Cvijanovich, Natalie Z., Quasney, Michael, Baines, Torrey D., Atreya, Mihir R., Nowak, Jeffrey, Genomics of Pediatric Septic Shock Investigators   +14 more
core   +1 more source

An overview of the mechanisms and potential roles of extracellular vesicles in septic shock

Frontiers in Immunology
Septic shock, a subset of sepsis, is a fatal condition associated with high morbidity and mortality. However, the pathophysiology of septic shock is not fully understood. Moreover, the diagnostic markers employed for identifying septic shock lack optimal
Meiling Cao, Mingyue Shi, Boru Zhou, Hongkun Jiang   +3 more
doaj   +1 more source

The interaction of vasopressin and corticosteroids in septic shock: a pilot randomized controlled trial.

, 2014
OBJECTIVES: Vasopressin and corticosteroids are both commonly used adjunctive therapies in septic shock. Retrospective analyses have suggested that there may be an interaction between these drugs, with higher circulating vasopressin levels and improved ...
Terblanche, Marius, Perkins, Gavin D., Brett, Stephen J., Gordon, Anthony C., Perkins, Gavin D, Stotz, Martin, Ashby, Deborah, Brett, Stephen J, Mason, Alexina J., Mason, Alexina J, Gordon, Anthony C   +10 more
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Sepsis and Septic Shock: Outcomes in Elderly and Very Elderly Intensive Care Patients

, 2022
Objective:The relationship between age and the development and outcome of sepsis and septic shock is unclear, especially in adults. There are few studies about the incidence, prognosis and mortality rates of sepsis in elderly and very elderly patients ...
Kamil İnci, Inci, KAMİL, Gülbin Aygencel, Melda Türkoğlu, Aygencel, Guelbin, Burcu Candemir, Candemir, Burcu, Turkoglu, Melda   +7 more
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Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]

, 2014
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
Vitón-Castillo, Adrián Alejandro, Mebazaa, A, Mebazaa, A. (Alexandre), Antonelli, M, Rhodes, A. (Andrew), Backer, D. (Daniel) de, Pinsky, MR, Teboul, JL, Bakker, J. (Jan), Vincent, JL, Pinsky, Michaël, Christoph Hofer, Jean Louis Vincent, Teboul, J.L. (Jean Louis), Beale, R, Daniel De Backer, Jaeschke, R, Rhodes, A, Jaeschke, Roman, Hofer, C, Jaeschke, R. (Roman), Teboul, Jean Louis, Mebazaa, Alexandre, Cecconi, M. (Maurizio), De Backer, Daniel, Antonelli, Massimo, Massimo Antonelli, Antonelli, M. (Massimo), Viruez-Soto, José Antonio, Bakker, Jan, Hofer, C. (Christoph), Auza-Santivañez, Jhossmar Cristians, Maurizio Cecconi, Vincent, J.-L. (Jean-Louis), Jean Louis Teboul, Roman Jaeschke, Beale, R. (Richard), Vincent, Jean Louis, Hofer, Christoph, Pinsky, M.R. (Michael), Michael R. Pinsky, Bakker, J, Richard Beale, Rhodes, Andrew, Alexandre Mebazaa, Luperón Loforte, Daysi, Cecconi, M, De Backer, D, Jan Bakker, Beale, Richard, Bakker, Jan; id_orcid, Cecconi, Maurizio, Andrew Rhodes   +52 more
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Characterization of Early Peripheral Immune Responses in Patients with Sepsis and Septic Shock

Biomedicines, 2022
(1) Background: Sepsis is a life-threatening condition caused by an abnormal host response to infection that produces altered physiological responses causing tissue damage and can result in organ dysfunction and, in some cases, death.
Jesús Beltrán-García, Rebeca Osca-Verdegal, Beatriz Jávega, Guadalupe Herrera, José-Enrique O’Connor, Eva García-López, Germán Casabó-Vallés, María Rodriguez-Gimillo, José Ferreres, Nieves Carbonell, Federico V. Pallardó, José Luis García-Giménez   +11 more
doaj   +1 more source

Septic shock

Journal of British Surgery, 1975
Abstract The problems associated with septic shock are highlighted, including those which arose during a 3-year prospective study. Mortality in the first year of the study was 71 per cent, falling to 38 per cent in the third year. The reasons, for this fall are detailed. The pattern of survival times changed over the 3 years, giving rise
openaire   +4 more sources