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An algorithm for mapping short reads to a dynamically changing genomic sequence
2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2010The constant advances in sequencing technology have redefined the way genome sequencing is performed. They are able to produce tens of millions of short sequences (reads), during a single experiment, and with a much lower cost than previously possible.
Tomás Flouri +3 more
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Innovations in Short-Read Sequencing Technologies and Their Applications to Clinical Genomics
Clinical ChemistryAbstract Background Massively parallel sequencing (MPS) of nucleic acids has been a transformative technology for basic and applied genomic science, increasing efficiencies and decreasing costs to enable studies of unprecedented scope and impact.
Katarzyna Polonis +5 more
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HLA Typing from Short-Read Sequencing Data with OptiType
2018The established standards for HLA genotyping rely on targeted DNA sequencing techniques. However, the increasing abundance of short-read sequencing data has prompted a demand for computational tools capable of HLA typing from general purpose sequencing data as well.
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Innovative technologies crowd the short-read sequencing market
Nature, 2023openaire +2 more sources