Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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Flicker perimetry in healthy subjects: influence of age and gender, learning effect and short-term fluctuation [PDF]
, 2007 Luciana Bernardi +2 more
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Does the short-term fluctuation of mineral element concentrations in the closed hydroponic experimental facilities affect the mineral concentrations in cucumber plants exposed to elevated CO2? [PDF]
, 2021 Xun Li +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Correlation between short-term and long-term intraocular pressure fluctuation in glaucoma patients
Clinical Ophthalmology, 2016 Naoki Tojo, Shinya Abe, Mari Miyakoshi, Atsushi Hayashi Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan Purpose: We investigated correlations between short-term and long ...
Tojo N, Abe S, Miyakoshi M, Hayashi A
doaj
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Estimating Seasonal and Short-Term Fluctuations in Evapo-Transpiration from Meadow Crops [PDF]
, 1958 LELAND T. PIERCE
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Sources of Fluctuations in Short-Term Yields and Recession Probabilities
, 2022 Andrea Ajello +4 more
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Stock mechanics: theory of conservation of total energy and predictions of coming short-term fluctuations of Dow Jones Industrials Average (DJIA) [PDF]
, 2006 Çağlar Tunçay
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