Results 191 to 200 of about 3,914,190 (307)

Crossing the Widom Line: Evolution of Cohesive Strength and Cavity Formation in Supercritical Water. [PDF]

J Phys Chem Lett
Niu J, Zhao Q, Adams MJ, Lu H, Chen Y, Wang X, Jin H, Guo L.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A Narrative Review of HRV Metric Selection for Applied Monitoring: RMSSD as the Default Metric for Sport and Exercise. [PDF]

J Funct Morphol Kinesiol
Esco MR.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Feasibility of short-term supine rehabilitation for pediatric orthostatic intolerance: a case series. [PDF]

J Phys Ther Sci
Ohnishi T, Mano T, Nishikawa H, Ozaki Y, Masuda T, Yoshida S.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Impact of Glycemic Trajectory and Variability on Ischemic Stroke Prognosis and Exploration of Its Mechanisms: A Comprehensive Review. [PDF]

Healthcare (Basel)
Wu X, Jin M, Geng G, Jin Y, Chen J.
europepmc   +1 more source

Part 4: Short Term Fluctuations

, 2021
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Modeling the rhythmic complexity of professional drumming with an oscillation-driven reservoir computer. [PDF]

Cogn Neurodyn
Kawai Y, Fujii S, Asada M.
europepmc   +1 more source